ID A0A9B0WWJ8_CHRAS Unreviewed; 696 AA.
AC A0A9B0WWJ8;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=ZNF750 {ECO:0000313|RefSeq:XP_006869670.1};
OS Chrysochloris asiatica (Cape golden mole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Chrysochloridae; Chrysochlorinae; Chrysochloris.
OX NCBI_TaxID=185453 {ECO:0000313|Proteomes:UP000504623, ECO:0000313|RefSeq:XP_006869670.1};
RN [1] {ECO:0000313|RefSeq:XP_006869670.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_006869670.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_006869670.1; XM_006869608.1.
DR AlphaFoldDB; A0A9B0WWJ8; -.
DR GeneID; 102818170; -.
DR CTD; 79755; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000504623; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000504623};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..57
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 64..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..696
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 74773 MW; 6D8E2ACB1BF7646B CRC64;
MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
RVPKCPKANS AEPKQTSPAD AKVASSRTAT NGLQHGFAKE DTKENLEMRT RTPHQPPAQK
LALPKDTVPR SPAPDAVPVL EGVGRPSAFV PVGEHRLQGS EHSDVPEMLA LPSPASKAAS
FHTKSAFHAP SYPWKAGSPF LPPEFPHKIP STKGFSALSP YAQSPLPEYP PHFYTEHGLA
TIYSPYLLPS APPEGDSALL SVYGAQEHRH FHPHPGPLPK HLSTPPSTYD HYRFFQQYHA
SLPLPYSFYR PESAFSAYGL KLPHLAGLAR DPSTHLLEET TLVYPNLSPS KLTPLSSHKK
NTEFGKESPS PQARDTTKDG QRETEGAKMS PRAGSAATGS PGRPSPTNFM QTSHACESLC
DLSSKPAPSP LGGLHPPEQI PIGSKPADCP SPQEPAQGAK SPGSLEEANE ELPSQTGGAS
PSLQGGSGAA PLNLSTKSVM AACGHTYRDA APLDTQNFPE LQDMPLDLSV KDACNALGPR
SSLRSPPREA ESAVAQETTD NPQEGPLGSE TGPDGPEEEP AEGAPGGRAS DERTVDSSDE
QKQTAAVALC QLAAYSPGKA RVDSEECSVR GPVTEQDTPV LSTKENRDTQ SSAPKPRAQK
RSQKDSGKSQ AGAKRTAPND TARVLTLRRR TRCLNA
//
