ID A0A9C6T601_DROAB Unreviewed; 1048 AA.
AC A0A9C6T601;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE SubName: Full=Collagen alpha-1(XVIII) chain isoform X1 {ECO:0000313|RefSeq:XP_051860243.1, ECO:0000313|RefSeq:XP_051860244.1};
GN Name=LOC117567544 {ECO:0000313|RefSeq:XP_051860243.1,
GN ECO:0000313|RefSeq:XP_051860244.1};
OS Drosophila albomicans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7291 {ECO:0000313|Proteomes:UP000515160, ECO:0000313|RefSeq:XP_051860243.1};
RN [1] {ECO:0000313|RefSeq:XP_051860243.1, ECO:0000313|RefSeq:XP_051860244.1}
RP IDENTIFICATION.
RC STRAIN=15112-1751.03 {ECO:0000313|RefSeq:XP_051860243.1,
RC ECO:0000313|RefSeq:XP_051860244.1};
RC TISSUE=Whole Adult {ECO:0000313|RefSeq:XP_051860243.1,
RC ECO:0000313|RefSeq:XP_051860244.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_051860243.1; XM_052004283.1.
DR RefSeq; XP_051860244.1; XM_052004284.1.
DR AlphaFoldDB; A0A9C6T601; -.
DR GeneID; 117567544; -.
DR CTD; 104327; -.
DR OrthoDB; 5983381at2759; -.
DR Proteomes; UP000515160; Chromosome 3.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000048; Multiplexin collagen isoform Ap3; 1.
DR FunFam; 3.40.1620.70:FF:000001; Multiplexin collagen isoform Ap3; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF1082; COLLAGEN TRIPLE HELIX REPEAT; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119,
KW ECO:0000313|RefSeq:XP_051860243.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000515160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1048
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5044697899"
FT DOMAIN 37..225
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT REGION 252..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1012..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..343
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..446
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..517
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..645
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 111142 MW; C21BC04F5A73CDEB CRC64;
MRSLLLVLWL AVPHLIAVLG ALEPELDDSN ETDKFGEHRL TDIITDEHYP SIKFGEGEDG
FPAFNFFSTA DVKSYSKVLL PQKLADFAIQ NTYKLSSLKG GYLFSVLRSM DDKVVQLGVH
LSPVIKNSYN VTLFYAQPDQ NDNVKIASYP IVHVPDKWNS IAFQVFSDNV VFFYDCKAVN
TTAIVRDPFE LSFASSSVLY IAQAGSQLGG NFEGFLQNIY LYTNPDAITM QCTAPPKPTV
ALQPDLDNEL TLDSKSESDV LSDTEVDTNS STDDSTADEN DLSNPEFWAG ATDNYDSSDL
QPPGQTEYML ERSHRGIKGE KGDRGPKGDS IRGPPGPPGP PGPKGETPVY PPFVETPSAG
AKYTGECTCN ATDILEAIKD NETLRETLRG PPGTQGRDGK TGAPGLTGAT GVTGARGPEG
IQGEKGEPGV DGMPGVMGPP GPPGAPGLPE SYDESLMGNS MGSLRSSTAT QAGPKGTTGD
KGEPGRPGDR GEKGHKGAHG PTGPKGEPGA PGLPGLAGQP GDGNGTKGER GEKGEKGMRG
RRGGTGAAGP IGPPGKPGPT GDIGHSGRPG ATGPKGDAGL KGAKGDAGGR EGAKGEKGDR
GSDGRDGLPG PPGLPATAGA GDGDSGGVQY IPMPGPPGPP GPPGLPGLSI TGPKGEAGMD
SRGSFFGDAS YYGRPGARSS LDELKALREL QDLRDRPDGT AEPPSQKAHS HKHGDSMGEG
EELPHLSASS SNMNMRIVPG AVTFQNIDEM TKKSAFSPPG TLAYITEEEA MLVRVNKGWQ
YIALGTLVPI ATPAPPTTVA PSLRFDLQSK NLLNSPPPLL NTPTFTTAPE YETWYPRMLR
VAALNEPYVG DLQGIRGADF ACYRQGRRAG LLGTFKAFLS SRVQNLDSIV RPADRDLPVV
NTRGDVLFNS WKGIFNGQGG FFSQAPRIYS FSGKNVLTDP LWPLRLVWHG SLPNGERSMD
TYCDAWHSGS HEKFGYASNL LGNKLLDQER QPCDGKLIVL CVEALSQDRR KKRDLSSPHS
HSHSRSRHSE LEFSTAEEYG EYLDNLLL
//
