ID A0A9C6WJB1_ARADU Unreviewed; 1240 AA.
AC A0A9C6WJB1;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 28-JAN-2026, entry version 15.
DE SubName: Full=Disease resistance protein At3g14460 isoform X4 {ECO:0000313|RefSeq:XP_052111916.1, ECO:0000313|RefSeq:XP_052111922.1};
GN Name=LOC110277731 {ECO:0000313|RefSeq:XP_052111916.1,
GN ECO:0000313|RefSeq:XP_052111922.1};
OS Arachis duranensis (Wild peanut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Arachis.
OX NCBI_TaxID=130453 {ECO:0000313|Proteomes:UP000515211, ECO:0000313|RefSeq:XP_052111916.1};
RN [1] {ECO:0000313|Proteomes:UP000515211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. V14167 {ECO:0000313|Proteomes:UP000515211};
RX PubMed=26901068; DOI=10.1038/ng.3517;
RA Bertioli D.J., Cannon S.B., Froenicke L., Huang G., Farmer A.D.,
RA Cannon E.K., Liu X., Gao D., Clevenger J., Dash S., Ren L.,
RA Moretzsohn M.C., Shirasawa K., Huang W., Vidigal B., Abernathy B., Chu Y.,
RA Niederhuth C.E., Umale P., Araujo A.C., Kozik A., Kim K.D., Burow M.D.,
RA Varshney R.K., Wang X., Zhang X., Barkley N., Guimaraes P.M., Isobe S.,
RA Guo B., Liao B., Stalker H.T., Schmitz R.J., Scheffler B.E.,
RA Leal-Bertioli S.C., Xun X., Jackson S.A., Michelmore R., Ozias-Akins P.;
RT "The genome sequences of Arachis duranensis and Arachis ipaensis, the
RT diploid ancestors of cultivated peanut.";
RL Nat. Genet. 48:438-446(2016).
RN [2] {ECO:0000313|RefSeq:XP_052111916.1, ECO:0000313|RefSeq:XP_052111922.1}
RP IDENTIFICATION.
RC TISSUE=Whole plant {ECO:0000313|RefSeq:XP_052111916.1,
RC ECO:0000313|RefSeq:XP_052111922.1};
RG RefSeq;
RL Submitted (APR-2025) to UniProtKB.
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DR RefSeq; XP_052111916.1; XM_052255956.1.
DR RefSeq; XP_052111922.1; XM_052255962.1.
DR AlphaFoldDB; A0A9C6WJB1; -.
DR GeneID; 110277731; -.
DR Proteomes; UP000515211; Chromosome 2.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProtKB-ARBA.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR FunFam; 1.10.10.10:FF:000322; Probable disease resistance protein At1g63360; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR056789; LRR_R13L1-DRL21.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR36766:SF51; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF25019; LRR_R13L1-DRL21; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000515211};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 37..101
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 163..331
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 417..485
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 666..792
FT /note="R13L1/DRL21-like LRR repeat region"
FT /evidence="ECO:0000259|Pfam:PF25019"
FT COILED 111..138
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1240 AA; 139976 MW; 79A3D40F60197E9A CRC64;
MAGVVVGGAF LSGFINVVLD RLISADAVNL VVGKKLSSDL VERLRNALTD TGALVDDAEL
KQLDNHDVKE WLNSLRDALY TADDLLDRIC TKAATQKGVR SFLPSFLNSE DRKMVNEIER
VVRRIEDLEN RKGKLGLEKI STASFSWKTP STSLVKGNVS GREDDKKALI KMLNDNNEHH
LSVISIVGMG GVGKTTLAQW MYNNAELMEG FDRKAWVCVS ENFNIVETTK NIVKQISTNT
QDLDSFNSIQ DALKKGLSKK KFFIVLDDVW SNDHHQWKDF LAPFQYGDKG STILLTTRKE
DVGSVVQTNC QPHYLIPLSE DYCWSVFAAN ASFPESNGSP ILAGIGKKIA KKFDGLPLAA
ETLGCLCRRH DAKEWEKILR SDIWGFSTND SKIVPALLIS YFHLAAHLKR CFVYCALFPK
DYHFKKDELI LLWMAEDLLR LPKRGESLEE VGCKCFKELV SRLFFKKLQD NNEYFVMHDL
LHDLAIFLAG DFYCRIEELG EQEEKKVLTR HFSYFPPGRL DRPISKVFNS NAKLESFRTS
LYIDDLFSME SVASKFICLR VLSFHKLDVL PDSIGESIHL RYLNLSSTDI NRLPESLCNL
YNLQTLILYG CTKLTMLPIN MHNLVNLRHL DIRKTCLEEM PGGISKMKHL HTLSSFVVGK
HEDNGIKELG GLSNLHGSLE LKKLENIVDV KEAENARMTN KNLMNELYLE WSSGDDMVPN
TKAERDILDS LQPHNCLREL TIKGYKGTIF PDWLGNCSYN NMTSVSLESC NNCCMLPSLG
QLPSLKALRI KGFGQLKCVD MEFYKGIGDP SFHIAPPFPL LESLEFDNMP CWEEWHLPDS
KAFPQLKSLQ IRDCPILNGD MLHQVFMRIV SSSLDALKVR KLVIIGFREG WLSARIPGMS
LNGDTLSIMG SESVVESAYN EMMSIKHLPS LQEVEIIECS FAVSWPNNCL LPKSLQKLTI
RECSKVEFPQ HKYDLVELLI SSCDSLTSLS LDVFPNLKNL DIHNCRNLES VSMSEAPHAA
LQRLSIAFCY KLVSLAGEGL AAPNLTRLQV VYCYKLEALP RDMNSLLPSL ESIGIFSCPN
ISRLAEGGLP PNLKSLAVGF CEQQMRDLSW MPNFHALTHL TILGCDCDTV TSYPEVGSLP
HLSSLTSLHI QEFDNLETLE CNELLRLTSL QELFIRSCKK LENMEGEKLP PSLLLLKIQD
CDLLEEHCKN KHQLIWPKIS HIPAIKFVDI WGDSQGDEGM
//
