ID A0A9D3MFL6_ANGAN Unreviewed; 405 AA.
AC A0A9D3MFL6;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 05-FEB-2025, entry version 8.
DE RecName: Full=Failed axon connections homolog {ECO:0008006|Google:ProtNLM};
GN ORFNames=ANANG_G00123090 {ECO:0000313|EMBL:KAG5847161.1};
OS Anguilla anguilla (European freshwater eel) (Muraena anguilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;
OC Anguilla.
OX NCBI_TaxID=7936 {ECO:0000313|EMBL:KAG5847161.1, ECO:0000313|Proteomes:UP001044222};
RN [1] {ECO:0000313|EMBL:KAG5847161.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tag_6206 {ECO:0000313|EMBL:KAG5847161.1};
RC TISSUE=Liver {ECO:0000313|EMBL:KAG5847161.1};
RA Henkel C., Jong-Raadsen S.A., Dufour S., Weltzien F.-A., Palstra A.P.,
RA Pelster B., Spaink H.P., Van Den Thillart G.E., Jansen H., Zahm M.,
RA Klopp C., Cedric C., Louis A., Berthelot C., Parey E., Roest Crollius H.,
RA Montfort J., Robinson-Rechavi M., Bucao C., Bouchez O., Gislard M.,
RA Lluch J., Milhes M., Lampietro C., Lopez Roques C., Donnadieu C.,
RA Braasch I., Desvignes T., Postlethwait J., Bobe J., Guiguen Y., Dirks R.;
RT "A chromosome-scale assembly of European eel, Anguilla anguilla.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG5847161.1}.
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DR EMBL; JAFIRN010000006; KAG5847161.1; -; Genomic_DNA.
DR OMA; YPLQDCG; -.
DR OrthoDB; 5809458at2759; -.
DR Proteomes; UP001044222; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR CDD; cd03080; GST_N_Metaxin_like; 1.
DR InterPro; IPR026928; FAX/IsoI-like.
DR InterPro; IPR045796; FAXC_N.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR050931; Mito_Protein_Transport_Metaxin.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR Pfam; PF19333; FAXC_N; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF17172; GST_N_4; 1.
DR SFLD; SFLDG01180; SUF1; 1.
DR SFLD; SFLDG01200; SUF1.1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP001044222}.
FT DOMAIN 1..104
FT /note="Failed axon connections homolog N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19333"
FT DOMAIN 115..208
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17172"
FT DOMAIN 260..322
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 366..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45910 MW; A1579524767D1B1A CRC64;
MYWGVGFASS RSCVVDLGRN QSFSFGLCGS NEHYSFYGYI VAFPLQDYGG IMSGLGSDSW
WKKTLYLTGG ALLAAAAYLL HELLAIRKEQ EMDSKDAIIL HQFSRPKSGV PSLSPFCLKL
ETYLRMVDLP YQNYFDGKLS PQGKMPWIEY NNEQVSGTEF IIDFLEEKLG VNLNKSLSPQ
EKAVSRAVTK MVEEHFYWTI AYCQWVDNLE ETQKMLAVSG PLSDLLKWIL SHLTGGIVKR
EMYGHGIGRF SKEEVYALME KDMRTLATLL GDKKYIMGPK MSTVDATVFG HLAQAMWTLP
GTRPEQLIKG ELINLAMYCE RIRRKFWPEW YVDIDDFYYD GSSESSGTPS RPLEFGLYSR
TETFEEDATG NSLSYSRTPD SECTAHSLMD SDLDMEGSDP ESLKC
//
