ID A0A9D3MNN0_ANGAN Unreviewed; 715 AA.
AC A0A9D3MNN0;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 18-JUN-2025, entry version 12.
DE RecName: Full=HMG box domain-containing protein {ECO:0000259|PROSITE:PS50118};
GN ORFNames=ANANG_G00089480 {ECO:0000313|EMBL:KAG5851103.1};
OS Anguilla anguilla (European freshwater eel) (Muraena anguilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;
OC Anguilla.
OX NCBI_TaxID=7936 {ECO:0000313|EMBL:KAG5851103.1, ECO:0000313|Proteomes:UP001044222};
RN [1] {ECO:0000313|EMBL:KAG5851103.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tag_6206 {ECO:0000313|EMBL:KAG5851103.1};
RC TISSUE=Liver {ECO:0000313|EMBL:KAG5851103.1};
RA Henkel C., Jong-Raadsen S.A., Dufour S., Weltzien F.-A., Palstra A.P.,
RA Pelster B., Spaink H.P., Van Den Thillart G.E., Jansen H., Zahm M.,
RA Klopp C., Cedric C., Louis A., Berthelot C., Parey E., Roest Crollius H.,
RA Montfort J., Robinson-Rechavi M., Bucao C., Bouchez O., Gislard M.,
RA Lluch J., Milhes M., Lampietro C., Lopez Roques C., Donnadieu C.,
RA Braasch I., Desvignes T., Postlethwait J., Bobe J., Guiguen Y., Dirks R.;
RT "A chromosome-scale assembly of European eel, Anguilla anguilla.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG5851103.1}.
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DR EMBL; JAFIRN010000004; KAG5851103.1; -; Genomic_DNA.
DR Proteomes; UP001044222; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21998; HMG-box_UBF1_rpt1-like; 1.
DR CDD; cd21999; HMG-box_UBF1_rpt2; 1.
DR CDD; cd22000; HMG-box_UBF1_rpt3; 1.
DR CDD; cd22002; HMG-box_UBF1_rpt5; 1.
DR CDD; cd22003; HMG-box_UBF1_rpt6-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 5.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR051762; UBF1.
DR PANTHER; PTHR46318:SF5; NUCLEOLAR TRANSCRIPTION FACTOR 1 ISOFORM X1; 1.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF14887; HMG_box_5; 2.
DR SMART; SM00398; HMG; 5.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47095; HMG-box; 5.
DR PROSITE; PS50118; HMG_BOX_2; 5.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP001044222};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 109..177
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 193..261
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 293..357
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 425..492
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 516..582
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 109..177
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 193..261
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 293..357
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 425..492
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 516..582
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 378..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 159..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 625..635
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..699
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..709
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 82927 MW; 50648D820EA3EBFB CRC64;
MNVNSSQATR LKAEPDDVWN KEDCLTLLER IRSLLPDGDG MKYKTTESHF DWDKVCFGSF
TGDMCKQKWQ KVSNEVRKFR TMTELIIDAT ECVKNPYKGK KLKTHPDFPK KPLTPYFRFF
MEKRAKYAKI HPEMSNLDLT KILSKKYKEL TEKKKLKYIQ EFHHEKESFE KNMARFKEQH
PELIEERKKS DLPEKPKTPQ QLWYNHEKKA YMKLHPDVGQ KELKEALRRQ WSQLSDKKRL
KWISKALELQ KAYEDSMRAY HKAHPDSSAD EHVKSVLTKA ERQLKDKFDG RPTKPPPNGY
SLYCAELMVN MKDVPSTERM VLCSKQWKMM TQKEKDMLQK RCEQKKKQYE VDLQRFLESL
PEEERDRVLT EEKLGGTRLN MGAAGTPLRA KSPSSKERAR DADLDQWVHG LAKKMRDGRK
RTRLPETPKT AEEMWQQSVI GDYLAKYRND RKKAQSAMVS AWKSMDKKEK IPWIKKAAED
QKRYEVQYST VKEVLDTRTP QSGQSKGKAK FDGEPKKPPV SGYQMFSQEL LTNGELNHFS
LKERMVEIGK RWHKLSQNQK DKYKKVVEEQ QIEYKAELEA WVKSLSPHER AVYKEVSSTK
RRSTAKAQGP RAKVRIMKAK AVGATAGGLG AGGGRRAMAY RAKQDTSDSD DDEEKTDSSD
SEEEDEEESS GSSDSDDDDD DDENDDDDDE DDDDDDDQSD PTSSSTGDSS ETDSD
//
