ID A0A9D3QES6_MEGAT Unreviewed; 210 AA.
AC A0A9D3QES6;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 28-JAN-2026, entry version 10.
DE RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};
GN ORFNames=MATL_G00043700 {ECO:0000313|EMBL:KAG7483946.1};
OS Megalops atlanticus (Tarpon) (Clupea gigantea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Elopiformes; Megalopidae; Megalops.
OX NCBI_TaxID=7932 {ECO:0000313|EMBL:KAG7483946.1, ECO:0000313|Proteomes:UP001046870};
RN [1] {ECO:0000313|EMBL:KAG7483946.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YG-15Mar2019-1 {ECO:0000313|EMBL:KAG7483946.1};
RC TISSUE=Brain {ECO:0000313|EMBL:KAG7483946.1};
RA Zahm M., Roques C., Cabau C., Klopp C., Donnadieu C., Jouanno E.,
RA Lampietro C., Louis A., Herpin A., Echchiki A., Berthelot C., Parey E.,
RA Roest-Crollius H., Braasch I., Postlethwait J., Bobe J., Montfort J.,
RA Bouchez O., Begum T., Mejri S., Adams A., Chen W.-J., Guiguen Y.;
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU210713}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004477,
CC ECO:0000256|RuleBase:RU210713}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG7483946.1}.
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DR EMBL; JAFDVH010000003; KAG7483946.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9D3QES6; -.
DR OrthoDB; 567788at2759; -.
DR Proteomes; UP001046870; Chromosome 3.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043005; C:neuron projection; IEA:TreeGrafter.
DR GO; GO:0014069; C:postsynaptic density; IEA:TreeGrafter.
DR GO; GO:0007420; P:brain development; IEA:TreeGrafter.
DR GO; GO:0071787; P:endoplasmic reticulum tubular network formation; IEA:TreeGrafter.
DR GO; GO:0030182; P:neuron differentiation; IEA:TreeGrafter.
DR Gene3D; 1.20.5.2480; -; 1.
DR InterPro; IPR003388; Reticulon.
DR InterPro; IPR046964; RTN1-4.
DR PANTHER; PTHR45799:SF7; RETICULON; 1.
DR PANTHER; PTHR45799; RETICULON-LIKE PROTEIN; 1.
DR Pfam; PF02453; Reticulon; 1.
DR PROSITE; PS50845; RETICULON; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU210713};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU210713};
KW Reference proteome {ECO:0000313|Proteomes:UP001046870};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU210713};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU210713}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU210713"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU210713"
FT DOMAIN 5..208
FT /note="Reticulon"
FT /evidence="ECO:0000259|PROSITE:PS50845"
FT REGION 187..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..201
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 210 AA; 23579 MW; 67ED2AEF102008D2 CRC64;
MASKVMDLIY WREMERTGIV FTGLVVGLLC MFQLSAVTVV SHLSLAVMCF TVPVRLLFKV
LELLRWSSGA HPFQSFLDTD STLTEDQTVF YVHRVVVMLA SGVTEIKRLL FVASLFDSLK
FILLMYLLTY VGVLCNGLTL LIIGVICVFS LPLFCKRQQE RIDKVVRAVT SCKNKIKNLF
RQLAQMAKRT PAPAPPPPPT HGPKSRAKSK
//
