ID A0A9D3WU59_9SAUR Unreviewed; 339 AA.
AC A0A9D3WU59;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 18-JUN-2025, entry version 10.
DE RecName: Full=Syntaxin-5 {ECO:0000256|ARBA:ARBA00072669};
GN ORFNames=KIL84_003444 {ECO:0000313|EMBL:KAH1167961.1};
OS Mauremys mutica (yellowpond turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Geoemydidae; Geoemydinae; Mauremys.
OX NCBI_TaxID=74926 {ECO:0000313|EMBL:KAH1167961.1, ECO:0000313|Proteomes:UP000827986};
RN [1] {ECO:0000313|EMBL:KAH1167961.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MM-2020 {ECO:0000313|EMBL:KAH1167961.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAH1167961.1};
RA Gong S., Gao Y.;
RT "The genome of Mauremys mutica provides insights into the evolution of
RT semi-aquatic lifestyle.";
RL Submitted (SEP-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates endoplasmic reticulum to Golgi transport. Together
CC with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and
CC fusion at the cis-Golgi membrane to maintain the stacked and inter-
CC connected structure of the Golgi apparatus.
CC {ECO:0000256|ARBA:ARBA00059412}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate
CC compartment membrane {ECO:0000256|ARBA:ARBA00060411}; Single-pass type
CC IV membrane protein {ECO:0000256|ARBA:ARBA00060411}. Golgi apparatus
CC membrane {ECO:0000256|ARBA:ARBA00004394}.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAH1167961.1}.
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DR EMBL; JAHDVG010000486; KAH1167961.1; -; Genomic_DNA.
DR OrthoDB; 421009at2759; -.
DR Proteomes; UP000827986; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:TreeGrafter.
DR GO; GO:0031201; C:SNARE complex; IEA:TreeGrafter.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0000149; F:SNARE binding; IEA:TreeGrafter.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:TreeGrafter.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0048278; P:vesicle docking; IEA:TreeGrafter.
DR GO; GO:0006906; P:vesicle fusion; IEA:TreeGrafter.
DR CDD; cd15844; SNARE_syntaxin5; 1.
DR FunFam; 1.20.5.110:FF:000187; SNARE domain containing protein; 1.
DR FunFam; 1.20.58.70:FF:000005; syntaxin-5 isoform X1; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR021538; Syntaxin-5_N.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF3; SYNTAXIN-5; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF11416; Syntaxin-5_N; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000827986};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 247..309
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 278..305
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 339 AA; 38374 MW; 5FB300D781FFECE5 CRC64;
MNTRKRHGSK NTDQGVYLGP SQIQELPPPA ATTVASSLSF PDTMSCRDRT QEFLSACKSL
QSRQNGLQLN KPALNAMRQR SEFTVIAKRI GKDLSNTFAK LEKLTILAKR KSLFDDKAVE
IEELTYIIKQ DINSLNKQIA QLQDFVRAKG SQSGRHVQTH SNTIVVSLQS KLASMSNDFK
SVLEVRTENL KQQRSRREHF SRTPIPLNAS NLGGSAMLQD EPRRAGDVAI DMDNRTSQQL
QLIDEQDSYI QSRADTMQNI ESTIVELGSI FQQLAHMVKE QEETIQRIDA NVEDAQLNVE
AAHSEILKYF QSVTSNRWLM VKIFLILIVF FIIFVVFLA
//
