ID A0A9D5D840_9LILI Unreviewed; 1466 AA.
AC A0A9D5D840;
DT 03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2023, sequence version 1.
DT 18-JUN-2025, entry version 10.
DE RecName: Full=Histone deacetylase interacting domain-containing protein {ECO:0000259|SMART:SM00761};
GN ORFNames=J5N97_004166 {ECO:0000313|EMBL:KAJ0985810.1};
OS Dioscorea zingiberensis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Dioscoreales; Dioscoreaceae;
OC Dioscorea.
OX NCBI_TaxID=325984 {ECO:0000313|EMBL:KAJ0985810.1, ECO:0000313|Proteomes:UP001085076};
RN [1] {ECO:0000313|EMBL:KAJ0985810.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Dzin_1.0 {ECO:0000313|EMBL:KAJ0985810.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAJ0985810.1};
RA Li Z., Yang C.;
RL Submitted (MAR-2021) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAJ0985810.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Dzin_1.0 {ECO:0000313|EMBL:KAJ0985810.1};
RX PubMed=36204203;
RA Li Y., Tan C., Li Z., Guo J., Li S., Chen X., Wang C., Dai X., Yang H.,
RA Song W., Hou L., Xu J., Tong Z., Xu A., Yuan X., Wang W., Yang Q., Chen L.,
RA Sun Z., Wang K., Pan B., Chen J., Bao Y., Liu F., Qi X., Gang D.R., Wen J.,
RA Li J.;
RT "The genome of Dioscorea zingiberensis sheds light on the biosynthesis,
RT origin and evolution of the medicinally important diosgenin saponins.";
RL Hortic Res 9:0-0(2022).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00810}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ0985810.1}.
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DR EMBL; JAGGNH010000001; KAJ0985810.1; -; Genomic_DNA.
DR OrthoDB; 10265969at2759; -.
DR Proteomes; UP001085076; Miscellaneous, Linkage group lg01.
DR GO; GO:0000785; C:chromatin; IEA:TreeGrafter.
DR GO; GO:0000118; C:histone deacetylase complex; IEA:TreeGrafter.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR FunFam; 1.20.1160.11:FF:000001; Paired amphipathic helix protein Sin3; 1.
DR FunFam; 1.20.1160.11:FF:000002; Paired amphipathic helix protein SIN3; 1.
DR FunFam; 1.20.1160.11:FF:000003; Paired amphipathic helix SIN3-like protein; 1.
DR Gene3D; 1.20.1160.11; Paired amphipathic helix; 3.
DR InterPro; IPR013194; HDAC_interact_dom.
DR InterPro; IPR003822; PAH.
DR InterPro; IPR036600; PAH_sf.
DR InterPro; IPR039774; Sin3-like.
DR InterPro; IPR031693; Sin3_C.
DR PANTHER; PTHR12346:SF0; SIN3A, ISOFORM G; 1.
DR PANTHER; PTHR12346; SIN3B-RELATED; 1.
DR Pfam; PF02671; PAH; 3.
DR Pfam; PF08295; Sin3_corepress; 1.
DR Pfam; PF16879; Sin3a_C; 1.
DR SMART; SM00761; HDAC_interact; 1.
DR SUPFAM; SSF47762; PAH2 domain; 3.
DR PROSITE; PS51477; PAH; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00810}; Reference proteome {ECO:0000313|Proteomes:UP001085076};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 493..593
FT /note="Histone deacetylase interacting"
FT /evidence="ECO:0000259|SMART:SM00761"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 562..589
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..285
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..454
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..857
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 948..963
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1049
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1066
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1095
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1466 AA; 166240 MW; FBE0AF27D060411B CRC64;
MKKGREDSYS SSQIKRPNSS TSGQTHMANS AAVSNSSKLT THDALAYLKA VKDIFHDTKE
KYDEFLEVMK DFKSQRIDTS GVIARVKELF KGHRDLILGF NTFLPKGYEI KLPAEEKKPV
EFQEAITFVN KIKNRFQNEE HVYKSFLDIL NMYRRENKSI TDVYEEVAAL FRDHPDLLDE
FTHFLPDTSA TGAQHNVTAT RPMFRWDGRP SIVPGLKLTS PGQRERTYNS HTERDLTVDR
PDLEHDRQRR RAEREKDRKE DRDKREHERD EKDLEHDSRD LDTMQRRRKP SRIGNDAAPE
QLHQGGEGAE NFATYSISTS SYDDKNALKS VYPQEVSYFD KVKEKLHPDG YQEFLKCIDI
YSKEIISKTE LKNLLCDVLE KYPDLMDGLD EIFANPGSID GFLTGVINKK SLWNEGHMTR
PVKGEERDRD REYERDDKDK ERERERERDR ERERLDKSVP FVSKDVGSQR STLAANKEKY
NLSKPISELD LSNCQRCTPS YRLLPKNYPT PPASHRTELG ASVLNDVWVS VTSGSEDYSF
KHMRKNQYEE SLFRCEDDRF ELDMLLESVN AATKRVEELL EKMQDNTIKM ESPIRLEDHF
TPLNLRCIER LYGDHGLDVM DVLRKNASLA LPVILTRLKQ KQEEWSRCRS DFNKVWAEIY
AKNYHKSLDH RSFYFKQQDT KSLSTKALLA EIKEINEKKR KEDDVLLAIA AGNRRPIIPN
VEFEYTDPDI HEDLYHIIKY SCGEVCASTD QLDKVLRIWT AFLEPLFGVL PRPQGAEDAV
DVVRTKSRAI KSNLVSVREN NGSPSAVVAG NTKQLNPIMN GDDGNLQEQG SLYKARLANG
DTPVNRNGFH DADRSAGRSD NPCSTPLHAK VQTTPVADEI SGITIQTAAA EQLVDNNSLA
SRGEQTQCRA NLENTSGSTN AKSGHAGAER VLETCANNEV LPLEGGENSR QVVSANGGSA
TESTKVRRYH DPSTSQNNLK VEREEGELSP NGDFEEDNFV VFENSAVDAV PKGKNSPSSR
QYQTKPGEVA CSSVAAGDND ADADDEGDES AQRSTEDSEN ASEAGEDVSG SESGDGEECS
REDHEEEDDD ADHDDPDGKA ESEGEAEGMV DAHDADEGTS LPFPERFLHT SKPLAKHVHE
ALHDKEDKCS RIFYGNDSFY VLFRLHQTLY ERILSAKINS STAERKWRTT KETSPPDLYA
KFMGALYNLL DGSADNTKFE DDCRAIIGTQ SYVLFTLDKL IYKVVKQLQA VASDDMDNKL
LQLYAYEKSR RPGRFMDVVY HENARVLLHD ESIYRFECTS SPTRLSIQLM EYGQEKAEVT
AVSIDPNFTA YLYNDFLSSD PDKKKRRAVF LGRNKRKFGT DEYSAYSTAM DGVRVVNGLE
CKISCNSSKV SYVLDTEDLL VRFVKKRRYS YGGVPTSKRI LPLEWDETST LTLHNVVEIT
TLQNPSCTYE AASCLGSLAS SDIDDV
//
