ID A0A9J6EWV7_RHIMP Unreviewed; 355 AA.
AC A0A9J6EWV7;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=BBSome complex member BBS5 PH domain-containing protein {ECO:0000259|SMART:SM00683};
GN ORFNames=HPB51_002852 {ECO:0000313|EMBL:KAH8038708.1};
OS Rhipicephalus microplus (Cattle tick) (Boophilus microplus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;
OC Rhipicephalus; Boophilus.
OX NCBI_TaxID=6941 {ECO:0000313|EMBL:KAH8038708.1, ECO:0000313|Proteomes:UP000821866};
RN [1] {ECO:0000313|EMBL:KAH8038708.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Rmic-2018 {ECO:0000313|EMBL:KAH8038708.1};
RX PubMed=32814014;
RG Tick Genome and Microbiome Consortium (TIGMIC);
RA Jia N., Wang J., Shi W., Du L., Sun Y., Zhan W., Jiang J.F., Wang Q.,
RA Zhang B., Ji P., Bell-Sakyi L., Cui X.M., Yuan T.T., Jiang B.G., Yang W.F.,
RA Lam T.T., Chang Q.C., Ding S.J., Wang X.J., Zhu J.G., Ruan X.D., Zhao L.,
RA Wei J.T., Ye R.Z., Que T.C., Du C.H., Zhou Y.H., Cheng J.X., Dai P.F.,
RA Guo W.B., Han X.H., Huang E.J., Li L.F., Wei W., Gao Y.C., Liu J.Z.,
RA Shao H.Z., Wang X., Wang C.C., Yang T.C., Huo Q.B., Li W., Chen H.Y.,
RA Chen S.E., Zhou L.G., Ni X.B., Tian J.H., Sheng Y., Liu T., Pan Y.S.,
RA Xia L.Y., Li J., Zhao F., Cao W.C.;
RT "Large-Scale Comparative Analyses of Tick Genomes Elucidate Their Genetic
RT Diversity and Vector Capacities.";
RL Cell 182:1328-1340(2020).
RN [2] {ECO:0000313|EMBL:KAH8038708.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Rmic-2018 {ECO:0000313|EMBL:KAH8038708.1};
RC TISSUE=Larvae {ECO:0000313|EMBL:KAH8038708.1};
RA Jia N., Wang J., Shi W., Du L., Sun Y., Zhan W., Jiang J., Wang Q.,
RA Zhang B., Ji P., Sakyi L.B., Cui X., Yuan T., Jiang B., Yang W.,
RA Lam T.T.-Y., Chang Q., Ding S., Wang X., Zhu J., Ruan X., Zhao L., Wei J.,
RA Que T., Du C., Cheng J., Dai P., Han X., Huang E., Gao Y., Liu J., Shao H.,
RA Ye R., Li L., Wei W., Wang X., Wang C., Huo Q., Li W., Guo W., Chen H.,
RA Chen S., Zhou L., Zhou L., Ni X., Tian J., Zhou Y., Sheng Y., Liu T.,
RA Pan Y., Xia L., Li J., Zhao F., Cao W.;
RL Submitted (SEP-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the BBS5 family.
CC {ECO:0000256|ARBA:ARBA00005822}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAH8038708.1}.
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DR EMBL; JABSTU010000001; KAH8038708.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9J6EWV7; -.
DR VEuPathDB; VectorBase:LOC119159708; -.
DR Proteomes; UP000821866; Chromosome 1.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0036064; C:ciliary basal body; IEA:TreeGrafter.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:TreeGrafter.
DR GO; GO:0060271; P:cilium assembly; IEA:TreeGrafter.
DR InterPro; IPR006606; BBL5.
DR InterPro; IPR014003; BBS5_PH.
DR PANTHER; PTHR21351:SF0; BARDET-BIEDL SYNDROME 5 PROTEIN; 1.
DR PANTHER; PTHR21351; BARDET-BIEDL SYNDROME PROTEIN 5; 1.
DR Pfam; PF07289; BBL5; 1.
DR SMART; SM00683; DM16; 2.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000821866}.
FT DOMAIN 28..82
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
FT DOMAIN 158..212
FT /note="BBSome complex member BBS5 PH"
FT /evidence="ECO:0000259|SMART:SM00683"
SQ SEQUENCE 355 AA; 39744 MW; 56DE04E39B15AC52 CRC64;
MTESEGLWQD RDIRFDISNQ DLQYGAGEEQ IDRLPNVEDT KGNSGDKGTL YVTNLRIIWQ
SLARPRVNLS VGFNCVTGIS TRTVNSKLCG IAEALYIMTK SNSTRYEFIF TNMTMEQPRL
IASVLNTFKA YSATKLYRDL HLRAALLHNR QLRLLPMEQL CSQVNGVWNL SSDQGNLGTM
HITNVRIVWH ANMNESFNIS LPYLQVAAIK TRESKFGTAL VIETTDRVSA LRCRRAESPQ
KEPAIGQALL GLLKVHKTKP IMGVDVFMQK QVYEEATTQD TGPEIQDEPE VNSADGTHYD
AFAKSVWLGM KLGDDLDSNQ KFLRNPTFRN RLGSSLRGDC GGYIAATSSK HSRGG
//
