ID A0A9J7BLH2_9BACT Unreviewed; 636 AA.
AC A0A9J7BLH2;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:UWZ83732.1};
GN ORFNames=MOP44_24600 {ECO:0000313|EMBL:UWZ83732.1};
OS Occallatibacter riparius.
OC Bacteria; Pseudomonadati; Acidobacteriota; Terriglobia; Terriglobales;
OC Acidobacteriaceae; Occallatibacter.
OX NCBI_TaxID=1002689 {ECO:0000313|EMBL:UWZ83732.1, ECO:0000313|Proteomes:UP001059380};
RN [1] {ECO:0000313|EMBL:UWZ83732.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 25168 {ECO:0000313|EMBL:UWZ83732.1};
RA Qiu L., Zhang Q.;
RT "Phylogenetic analysis of Acidobacteriaceae.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP093313; UWZ83732.1; -; Genomic_DNA.
DR RefSeq; WP_260793113.1; NZ_CP093313.1.
DR AlphaFoldDB; A0A9J7BLH2; -.
DR KEGG; orp:MOP44_24600; -.
DR Proteomes; UP001059380; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:UWZ83732.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP001059380}.
FT DOMAIN 13..189
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 636 AA; 67939 MW; 2AAA01E5CF348FC3 CRC64;
MKSLGTVVSG EQPRYVVVGT AGHIDHGKTA LVYALTGTDT DRLPEEKQRG ITIDLGFAAL
DLENGEGGAL HLSLIDVPGH DAFIRNMLAG TGGIDCVMLV IAADEGVKAQ TEEHLAICSL
LGIQRGVVAL TKADAVSLEK LAETRASARR FLEGTFLEGA PIVPVSALKR EGIDELKSAL
VKVVREIPVR NDDFVARLPL DRSFSIKGFG TVVTGTLHSG VLRAGQVLEQ HPGGKQLRVR
GMQVHGSDAD AAHAPCRVAL NLAGVQVADM ARGDTLSIPG TLGPAMNVDV EITMLSGAPA
LKHGARVRVH AFTSDTLAKV LRFDQRDAGP NALVRLRLMK PLLLVPGDRI VLRRCSPEVT
IGGARVLDAS APAGARKAAA LAWLKLLRAA DDDEQLRLRI ARRGFDGITI SALTVETGLT
AEALQRRASP LLSAGTIAAA HGAESCWISA ESLNLAMQAV LRVLGESGPL SKAELRSRAR
LNTAVFALVV ERLTASGKLM VSGESVRLSG QEDELPESKR RQMQSIEKIY ADAGLAAPLL
SEVMSRMSVA PTAMRELMVL LMRSKRLVRM GADDAFVHPD ALAKLYADLR KHRGESFDVG
RFKSFTGLTR KHAIPLLEHL DQARVTRNNG GTRVVL
//
