ID A0A9J7N592_BRAFL Unreviewed; 983 AA.
AC A0A9J7N592;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 18-JUN-2025, entry version 12.
DE SubName: Full=Ataxin-2-like protein isoform X7 {ECO:0000313|RefSeq:XP_035690500.1};
GN Name=LOC118425635 {ECO:0000313|RefSeq:XP_035690500.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739 {ECO:0000313|Proteomes:UP000001554, ECO:0000313|RefSeq:XP_035690500.1};
RN [1] {ECO:0000313|Proteomes:UP000001554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|Proteomes:UP000001554};
RX PubMed=32313176;
RA Simakov O., Marletaz F., Yue J.X., O'Connell B., Jenkins J., Brandt A.,
RA Calef R., Tung C.H., Huang T.K., Schmutz J., Satoh N., Yu J.K.,
RA Putnam N.H., Green R.E., Rokhsar D.S.;
RT "Deeply conserved synteny resolves early events in vertebrate evolution.";
RL Nat. Ecol. Evol. 0:0-0(2020).
RN [2] {ECO:0000313|RefSeq:XP_035690500.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035690500.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035690500.1};
RG RefSeq;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ataxin-2 family.
CC {ECO:0000256|ARBA:ARBA00007503}.
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DR RefSeq; XP_035690500.1; XM_035834607.1.
DR GeneID; 118425635; -.
DR Proteomes; UP000001554; Chromosome 11.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-ARBA.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR InterPro; IPR045117; ATXN2-like.
DR InterPro; IPR009604; LsmAD_domain.
DR InterPro; IPR009818; PAM2_motif.
DR InterPro; IPR025852; SM_dom_ATX.
DR PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR PANTHER; PTHR12854:SF7; ATAXIN-2 HOMOLOG; 1.
DR Pfam; PF06741; LsmAD; 1.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF14438; SM-ATX; 1.
DR SMART; SM01272; LsmAD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001554}.
FT DOMAIN 195..262
FT /note="LsmAD"
FT /evidence="ECO:0000259|SMART:SM01272"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..320
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..574
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..849
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..983
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 983 AA; 106492 MW; 869D0D3033C59C80 CRC64;
MNKRSKRPSA GRFGGMTQNQ PRTGGRNLKG PVAQNVQGQN APLEGVYANS RLIHIATSLV
GNVVQVQVKD GSIYEGVFRT MSPKMEVVLE LAHKVEVGQT SLPSRDQLQE KLIFHQENVV
MLTALDVDLD YATKADSFTD AAISKFNGQI AEKELQPWEA DSDQAPDLLL DADGGTVSSN
GWDAAEMFRT NEKRYGVQSS YDSSLAGYTT QLKEEDTKEY REKRDRAQRI ADEIERSTDY
QRRVALEVHD DEEAAFSAVH RPSRNDGGGD LHNRYVPPHM RKDTSRGRGQ QMSPKPQRTG
HHGPGGMGPR GSPRAGAGSP HTVGTHPHAV SPQNRRPGGV PPHASSQAPQ HGPPPASSAK
NDSNSIPPTV NGEASIPQPS PVAPGQPDGS KHPASEVVSR NVPRRDDLNK PALPPAQANA
PHPSSTIYSN TERKNTTAKG LTPQLTSLKK FSEEFRLSEG TNKHDPKPKA EEIKDTKELS
KDASLSKDKE SSTTVKEERK ESKATETVPM KEGDQKGDKS QDNPKQGEGI SDVSSRTVKK
SQLNPNAKEF NPSAKPFVPA AAAISSAPRA RNQTPTPPRP QTQSPVVMQQ QGPMIVHGTP
LFTSVPSYGI VSTGSTMTMT GHPTFVGPIY AQQQQKTIYA KKVLPHWEWA ESHTGQTQAL
SAASENPVPT SVMAHQQRSD GHPPQTGPVT PLISPGPYQQ QFVQYPQGIV GPGQTMMPQQ
APGYPQQTMY PMVQGTARMV TPQQMQLQNA HPPQGYPTDQ HSAPMFVHSA GTMQGGQQIY
QQAAQVHHHA QPPPHLTQGH PNASQQHASP QPQSSVMQQQ QQQSNHPTPS PVHQQGHGQG
QGQAQQQHMP QQLVYHMPQQ MIPAGNQAHS QSSQTLHHHS MGPGQQPQFA PHAAGAPVTH
MTQAHGQHPH PQAQMVLVPQ VRKAQMSGQG HSPTSAPHGA IAAIPASSAA TAQMTPQYLT
HAQGQQRTSH HQQPPMQAYQ QGN
//
