ID A0A9K3ELX7_HELAN Unreviewed; 952 AA.
AC A0A9K3ELX7;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 28-JAN-2026, entry version 13.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolase, leucine-rich repeat domain superfamily {ECO:0000313|EMBL:KAF5775775.1};
GN ORFNames=HanXRQr2_Chr13g0615841 {ECO:0000313|EMBL:KAF5775775.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:KAF5775775.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5775775.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775775.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:KAF5775775.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775775.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF5775775.1}.
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DR EMBL; MNCJ02000328; KAF5775775.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9K3ELX7; -.
DR Gramene; mRNA:HanXRQr2_Chr13g0615841; mRNA:HanXRQr2_Chr13g0615841; HanXRQr2_Chr13g0615841.
DR Proteomes; UP000215914; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProtKB-ARBA.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR055414; LRR_R13L4/SHOC2-like.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR36766:SF61; NB-ARC DOMAIN DISEASE RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF23598; LRR_14; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:KAF5775775.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 171..233
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 234..315
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 402..470
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 546..881
FT /note="Disease resistance R13L4/SHOC-2-like LRR"
FT /evidence="ECO:0000259|Pfam:PF23598"
SQ SEQUENCE 952 AA; 108692 MW; 7406FD46C8521A1F CRC64;
MAEAAAAALV KVIFEKLADE AFKKYARSKN IHSELKQLGS TLSQIQALLN DASDKEITDE
SVRLWLNSLQ HLAYDIDDVL DDVATEAMHR ELTPESEAST SMVRKLIPTC CTKFSLSHRL
SPKLDSITTR LRYLEKQKAD LGLIVKEEKP KNTSRRNETS LLESNVVGRE GEKKRLLNQL
LVGESSKEKF SILPIVGLGG VGKTTLARIF YNDTRVKDHF ELMAWVCVSD EFDLQIALRE
QFKDKRFLLV LDDVWNQNYD DWEILVRPFH SGAAGSRVIM TTHQQDLLKK IGFNHVDNLE
SLSHEDALSL LALHALDVDN FDSHETLKPQ AKGIVKKCGA LPLALKAIGR LLRTKTEGEE
WDDVLKSEIW DLENADAIVP ALRLSYHDLS VDLKRLFAYC SLFPKDFMFD KEELILLWIA
EGYLNESTAD KSPERLGQEY FEKLLSRSFF QPAPNGESFF VMHDLMNDLA AFVAGEYFLR
FENQTEMAME ALAKYRHMSF MRERYVGFQK FEAFQRARSL RTLLAVYVGV EQSWNTLYIS
NKILVDLLPQ LPLLRVLSLR RFNISEVPDA ICSLNHLRYL NLSRTNISKL PENVGNLYNL
QTLIVFGCES LSTLPKSFLK LKKLRHFDIR DTPHLKKLPL GIGELKNLQT LPKVIVGGDG
DFAITKLKGL ENLRGELSIE GLQKVQIPMH AREANVSQKR LTKLKMKWGN DSQRGSLEKE
VLAELKPHTD TLKHFEVEYY GGVEFPCWVG DPTFHQLVHV SLRGCRKCTS LPLLGRLPSL
KELLIQGMDD VKVISLELSR STDVTFPSLE ILRFEDMSSW KAWSTNSEVM FPRLRELQII
KCPDLIDVSL EALPSLRVLR IEGCSESVLR SLVQAASSTT KLEIESILGL TDEVWRGVIV
NFWAVEELCI RKCDEIRYLW ESDAEASKVL ERKRRMRITL VATSYHLLGC WL
//
