ID A0A9K3EM50_HELAN Unreviewed; 954 AA.
AC A0A9K3EM50;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=Virus X resistance protein-like, coiled-coil {ECO:0000313|EMBL:KAF5775880.1};
GN ORFNames=HanXRQr2_Chr13g0616981 {ECO:0000313|EMBL:KAF5775880.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:KAF5775880.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5775880.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775880.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:KAF5775880.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775880.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF5775880.1}.
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DR EMBL; MNCJ02000328; KAF5775880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9K3EM50; -.
DR Gramene; mRNA:HanXRQr2_Chr13g0616981; mRNA:HanXRQr2_Chr13g0616981; HanXRQr2_Chr13g0616981.
DR Proteomes; UP000215914; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProtKB-ARBA.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR056789; LRR_R13L1-DRL21.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR36766:SF61; NB-ARC DOMAIN DISEASE RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF25019; LRR_R13L1-DRL21; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..91
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 174..339
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 440..505
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 682..809
FT /note="R13L1/DRL21-like LRR repeat region"
FT /evidence="ECO:0000259|Pfam:PF25019"
FT COILED 28..55
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 954 AA; 108226 MW; 7A142EEB4F0BCA24 CRC64;
MAETIATELI KVLFQKLSDE AFKRIARAQG IHNELKELKS TLSRIQDLLS DASQKEVTHK
SVKSWLNALQ HLAYDINDVL DDLATEDMHR ELTLESRAII CSKVRKLIPS CCTNFSLTHR
LSPKLDSINR ELENLEKQKT DLGLLKIDEK PRNTSRRRET SLPERDVVGR EVEKEQFLNK
LLGDDGSSQD NFSVLPIVGM GGVGKTTLAR LLYNDTKVQD YFEPKAWVCV SDDFDIFKIT
DAILQDVTKE NKKFKDLNQL QKALSEQFKD KRFLLVVDDV WSEKYADWEN LVRPFLSCAP
GSRIIMTTRK NQLLKQIGLH NVDHLESLPN EDALRLFAIH ALGVDNFNSH TTLKPQAEGI
VKKCGRLPLA LKAIGRLLRT KTDREDWDDV LNSEIWDVEI GNATESGKDV ENSDKIVPAL
RISYHELSAD LKQLFAYCSL FPKDFLFDKE ELVSLWMAEG FLNPSKSPER LGREYFEILL
SRSFFQHAPN DESLFIMHDL MNDLATFVAG EFFLRFDNHM KTKTEALAKY RHMSFTREEY
VGYQKFEAFK GAKSLRTFLA VSLGVDKGWV SYYLSSKILD DLLPELTLLR VLSLSRFQIS
EVPEFIGTLK HLRYLNLSRT NIKELPENVG NLYNLQTLIV SELRHLDIRD TPLEKLPLGI
GELESLQTLT KIIIEGNDGF AINELKGLTN LHGKVSIEGL HKVQSAKHAR EANLSLKKIT
GLELQWVDVF DGSRTDTLEE EVLNELKPNS DTLKTLSMVS YGGTQISNWV GDRSFHELVN
VSIRGCKKCT SLPPFGLLPS LKRLHIQGMD EVKLIGLELT GNDVNAFRSL EVLTFEDMSG
WEGWSTKNEG SAAVFPCLKE LYVKNCPQLI NVSLQALPSL KVLRIDTCGD GVLRSLVQVA
SSVTKLTISC VSGLIYEVWR GVIGYLKEVE DLSIEECNEI EYLWESETEA KRGG
//
