ID A0A9K3EM86_HELAN Unreviewed; 868 AA.
AC A0A9K3EM86;
DT 28-JUN-2023, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2023, sequence version 1.
DT 28-JAN-2026, entry version 14.
DE SubName: Full=Virus X resistance protein-like, coiled-coil {ECO:0000313|EMBL:KAF5775877.1};
GN ORFNames=HanXRQr2_Chr13g0616951 {ECO:0000313|EMBL:KAF5775877.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:KAF5775877.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5775877.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775877.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:KAF5775877.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5775877.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF5775877.1}.
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DR EMBL; MNCJ02000328; KAF5775877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9K3EM86; -.
DR Gramene; mRNA:HanXRQr2_Chr13g0616951; mRNA:HanXRQr2_Chr13g0616951; HanXRQr2_Chr13g0616951.
DR Proteomes; UP000215914; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProtKB-ARBA.
DR FunFam; 3.40.50.300:FF:001091; Probable disease resistance protein At1g61300; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR056789; LRR_R13L1-DRL21.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR058922; WHD_DRP.
DR PANTHER; PTHR36766:SF61; NB-ARC DOMAIN DISEASE RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF25019; LRR_R13L1-DRL21; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR Pfam; PF23559; WHD_DRP; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 173..341
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 442..507
FT /note="Disease resistance protein winged helix"
FT /evidence="ECO:0000259|Pfam:PF23559"
FT DOMAIN 655..782
FT /note="R13L1/DRL21-like LRR repeat region"
FT /evidence="ECO:0000259|Pfam:PF25019"
FT COILED 28..55
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 868 AA; 98284 MW; 140C9F06B77144A1 CRC64;
MAEAIATELV KVLFQKLSDE AFKRIARAQG IHNELKELKS TLSRIQDLLN DASQKEVTHK
SVKSWLNALQ HLAYDINDVL DDLATEDMHR EPTLESRAII CSKVRKLIPS CCTNFSLTHR
LSPKLDSINR DLENLEKRKT DLGLLKIDEK PRNTSRRSET SLPERDVVGR EVEKEQLLKK
LLGDDDGSSQ DNFSVLPIVG MGGVGKTTLA RLLYNDTKVQ DHFEPKAWVC VSDDFDIFKI
SNTIFQSVTT TKNEKFEDLD KLQIAIAEQF KGKRFLLVVD DVWSENYGDW ENLVRPFLSC
APGSRIIMTT RKEQLLKQIG FHNVDRLKSL SSEDALRLFA VHALGVDNFD SHTTLKPQGE
GIVKKCGCLP LALKAIGRLL RTKTDREDWD EVLNSEIWDV EIGNATESGK DVENSDKIVP
ALRISYHELS ADLKQLFAYC SLFPKDFLFD KEELVSLWMA EGFLNPSKSP ERLGREYFEI
LLSRSFFQHA PNDESLFIMH DLMNDLATFV AGEFFLRFDN HMETNPEALV KYRHMSFTRE
EYVGYQKFEA FKGAKSLRTF LAVSPGVDKG WGYCYLSSKI LDDLLPELTL LRVLSLSRFQ
ISEVPEFIGT LKHLRLRHLD IRHTPLEKLP LGIGELESLQ TLSKIIIEGD DGFAINELKG
LTNLHGKVSI EGLHKVQSAK HAREANLSLK KITGLELQWV DVFDGSRTDT LEEEVLNELK
PNSDTLKTLS MVSYGGTQIS NWVGDRSFHE LVDVSIRGCK KCTSLPPFGL LPSLKRLHIQ
GMDEVKLIGL ELTGNDVNAF RSLEVLTFED MSGWERWSAK NEGSAAVFPC LKELYVKKCP
QLINVSLQAL PSLKVLEIDR CGDGVAYT
//
