ID A0A9N8VPJ6_9GLOM Unreviewed; 433 AA.
AC A0A9N8VPJ6;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 6.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000256|HAMAP-Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255};
DE Short=eIF3e {ECO:0000256|HAMAP-Rule:MF_03004};
GN Name=INT6 {ECO:0000256|HAMAP-Rule:MF_03004};
GN ORFNames=POCULU_LOCUS401 {ECO:0000313|EMBL:CAG8457954.1};
OS Paraglomus occultum.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Paraglomerales; Paraglomeraceae; Paraglomus.
OX NCBI_TaxID=144539 {ECO:0000313|EMBL:CAG8457954.1, ECO:0000313|Proteomes:UP000789572};
RN [1] {ECO:0000313|EMBL:CAG8457954.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IA702 {ECO:0000313|EMBL:CAG8457954.1};
RA Kallberg Y., Tangrot J., Rosling A.;
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex, which is involved in protein synthesis of a
CC specialized repertoire of mRNAs and, together with other initiation
CC factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC ribosome. The eIF-3 complex specifically targets and initiates
CC translation of a subset of mRNAs involved in cell proliferation.
CC {ECO:0000256|HAMAP-Rule:MF_03004}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03004,
CC ECO:0000256|PIRNR:PIRNR016255}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03004,
CC ECO:0000256|PIRNR:PIRNR016255}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit E family. {ECO:0000256|HAMAP-
CC Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG8457954.1}.
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DR EMBL; CAJVPJ010000020; CAG8457954.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9N8VPJ6; -.
DR OrthoDB; 417252at2759; -.
DR Proteomes; UP000789572; Unassembled WGS sequence.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0071540; C:eukaryotic translation initiation factor 3 complex, eIF3e; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR CDD; cd21378; eIF3E; 1.
DR HAMAP; MF_03004; eIF3e; 1.
DR InterPro; IPR016650; eIF3e.
DR InterPro; IPR019010; eIF3e_N.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10317; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E; 1.
DR Pfam; PF09440; eIF3_N; 1.
DR Pfam; PF21357; EIF3E_C; 1.
DR Pfam; PF01399; PCI; 1.
DR PIRSF; PIRSF016255; eIF3e_su6; 1.
DR SMART; SM01186; eIF3_N; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03004};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540, ECO:0000256|HAMAP-
KW Rule:MF_03004};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_03004}; Reference proteome {ECO:0000313|Proteomes:UP000789572}.
FT DOMAIN 219..392
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 433 AA; 50814 MW; 18E9F9F23E0D20C4 CRC64;
MADYDLTPRM IPYLDRHLVF PLLEFLQLNE IYPAKDLYKA KYDLLAKTNM VDFIADLHKR
INETEETPEE FTRKREEVLQ TLQEFQSEAQ KVLDIIENPE VLANLRQDKL QNLHYLEKNF
GLTEEMANTL YQLAQFQYNC GNYGGASDML YHFRILSTDN ELNLSALWGK LASDILDVNW
EAALEELQRL RETIDSRPVV SPLHQLQQRT WFIHWSIFVF FNHPKGRDDI IDLFLQTQYI
NTIQTSCPWI LRYLTTAVVT NKRRKNILKD LIKIIQQESY EYRDPITEFI ESLYIKFDFE
GAQKKLKECE EVLRSDFFLV ATKNDFIENA RYLISETYCR IHLKIDISGL SKTLNLSPEA
GEKWIVNLIR DTRVDAKIDF KENTVVMNKI HTPICQQVIE RTRGLSFRSQ VLASTIEKHE
AQNAAALAEA VIE
//
