ID   A0A9P3PXL1_LYOSH        Unreviewed;       371 AA.
AC   A0A9P3PXL1;
DT   13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2023, sequence version 1.
DT   08-OCT-2025, entry version 12.
DE   RecName: Full=GDP-mannose transporter {ECO:0000256|RuleBase:RU367097};
DE            Short=GMT {ECO:0000256|RuleBase:RU367097};
GN   Name=VRG4 {ECO:0000313|EMBL:GLB43443.1};
GN   ORFNames=LshimejAT787_1303440 {ECO:0000313|EMBL:GLB43443.1};
OS   Lyophyllum shimeji (Hon-shimeji) (Tricholoma shimeji).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae; Lyophyllum.
OX   NCBI_TaxID=47721 {ECO:0000313|EMBL:GLB43443.1, ECO:0000313|Proteomes:UP001063166};
RN   [1] {ECO:0000313|EMBL:GLB43443.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AT787 {ECO:0000313|EMBL:GLB43443.1};
RA   Kobayashi Y., Shibata T., Hirakawa H., Shigenobu S., Nishiyama T.,
RA   Yamada A., Hasebe M., Kawaguchi M.;
RT   "The genome of Lyophyllum shimeji provides insight into the initial
RT   evolution of ectomycorrhizal fungal genome.";
RL   Submitted (JUL-2022) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the import of GDP-mannose from the cytoplasm into
CC       the Golgi lumen. {ECO:0000256|RuleBase:RU367097}.
CC   -!- SUBUNIT: Homooligomer. {ECO:0000256|RuleBase:RU367097}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004439, ECO:0000256|RuleBase:RU367097}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004439,
CC       ECO:0000256|RuleBase:RU367097}. Golgi apparatus membrane
CC       {ECO:0000256|RuleBase:RU367097}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU367097}. Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU367097}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU367097}.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. SLC35D subfamily.
CC       {ECO:0000256|RuleBase:RU367097}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GLB43443.1}.
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DR   EMBL; BRPK01000013; GLB43443.1; -; Genomic_DNA.
DR   OrthoDB; 417037at2759; -.
DR   Proteomes; UP001063166; Unassembled WGS sequence.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013657; SCL35B1-4/HUT1.
DR   InterPro; IPR050186; TPT_transporter.
DR   NCBIfam; TIGR00803; nst; 1.
DR   PANTHER; PTHR11132; SOLUTE CARRIER FAMILY 35; 1.
DR   Pfam; PF08449; UAA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW   ECO:0000256|RuleBase:RU367097};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU367097};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW   ECO:0000256|RuleBase:RU367097};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367097};
KW   Reference proteome {ECO:0000313|Proteomes:UP001063166};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367097};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367097}.
FT   TRANSMEM        38..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        65..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        98..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        121..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        152..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        203..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        274..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
FT   TRANSMEM        329..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367097"
SQ   SEQUENCE   371 AA;  40065 MW;  611ABDB12413E628 CRC64;
     MVARDRAPEG QDDAAAVKKA LATGASSKEP QGPAVPPILC YCCASILMTL VNKFVVSGAD
     FSMNFLLLAL QSMVCVSCVL FAKKVGLIRF RRFDSKDAKA WFPISVLLVS VIYTGSKSLQ
     FLSIPVYTIF KNLTIILIAY GEVLWFDGRV TGLTFVSFIL MVISSIIAAW ADIAEALESP
     LSPVNAASSL ETFTGVVHEL NVGYFWMLVN CLTSAGYVLA MRKRIKATGF SDWDSMFYNN
     LLCIPVLVVC SIVVEDWGRE SLARNFPQET RTFLLVAVAF SGAAAVGISY TTAWCIRVTS
     STTYSMVGAL NKLPVAASGM LFFGDPVTLG SVSAVGVGFV AGLLYSVAKN NQKKMEHRKE
     ADAIIPLCPV T
//