ID A0A9P4GCA3_9PLEO Unreviewed; 386 AA.
AC A0A9P4GCA3;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 10-JUN-2026, entry version 12.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:KAF1842575.1};
GN ORFNames=K460DRAFT_293505 {ECO:0000313|EMBL:KAF1842575.1};
OS Cucurbitaria berberidis CBS 394.84.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Cucurbitariaceae;
OC Cucurbitaria.
OX NCBI_TaxID=1168544 {ECO:0000313|EMBL:KAF1842575.1, ECO:0000313|Proteomes:UP000800039};
RN [1] {ECO:0000313|EMBL:KAF1842575.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 394.84 {ECO:0000313|EMBL:KAF1842575.1};
RG DOE Joint Genome Institute;
RA Haridas S., Albert R., Binder M., Bloem J., Labutti K., Salamov A.,
RA Andreopoulos B., Baker S.E., Barry K., Bills G., Bluhm B.H., Cannon C.,
RA Castanera R., Culley D.E., Daum C., Ezra D., Gonzalez J.B., Henrissat B.,
RA Kuo A., Liang C., Lipzen A., Lutzoni F., Magnuson J., Mondo S., Nolan M.,
RA Ohm R., Pangilinan J., Park H.-J., Ramirez L., Alfaro M., Sun H., Tritt A.,
RA Yoshinaga Y., Zwiers L.-H., Turgeon B.G., Goodwin S.B., Spatafora J.W.,
RA Crous P.W., Grigoriev I.V.;
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF1842575.1}.
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DR EMBL; ML976618; KAF1842575.1; -; Genomic_DNA.
DR RefSeq; XP_040785138.1; XM_040929425.1.
DR AlphaFoldDB; A0A9P4GCA3; -.
DR GeneID; 63846677; -.
DR OrthoDB; 5399569at2759; -.
DR Proteomes; UP000800039; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:TreeGrafter.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:L-tyrosine biosynthetic process; IEA:InterPro.
DR FunFam; 1.10.3660.10:FF:000002; Prephenate dehydrogenase [NADP(+)]; 1.
DR FunFam; 1.10.3660.10:FF:000004; Prephenate dehydrogenase [NADP(+)]; 1.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR050812; Preph/Arog_dehydrog.
DR InterPro; IPR003099; Prephen_DH.
DR InterPro; IPR012385; Prephenate_DH_fun.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF27505; 6PGD_Tyr1_C; 1.
DR Pfam; PF20463; PDH_C; 1.
DR PIRSF; PIRSF036510; PDH_fung; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000800039}.
FT DOMAIN 1..243
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 386 AA; 43790 MW; 524D6B0DA0C14833 CRC64;
MLRLRQPKVE IMQSGHFVSR CSDYIIYSVE AKNIDAVVKA FGPSTKVGAI VGGQTSCKAP
EMEAFERHLP KDVSIVSVHS LHGPGLDPKG QPLVLIKYRA SDADFAFVEK VMSCLGSKHV
YLTAEQHDRI TADTQAVTHA AFLSMGGAWF ANNQFPWDSS RYVGGIENVK MNITLRIYSN
KWHVYAGLAI LNPDAKKQIK QYAESVTELF KLMLAGQRDE LRERVHTARK AVFGDNHDGK
KLLLRDDLLD KFALGTIPEK KLKNNHLSLL AMVDCWWKLG IVPYDHMICS TPPSRMWLGI
TEYLFRNPTL LEEAIDTAID DNTFRADDLE FTFAARDWSS RVSLGNFDGY REKFERIQKY
FEPRFPEATK LGNEMIKVIL QNTQDP
//
