ID A0A9P4YXP0_9HYPO Unreviewed; 751 AA.
AC A0A9P4YXP0;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE SubName: Full=Choline kinase {ECO:0000313|EMBL:KAF4124407.1};
GN ORFNames=GMORB2_5073 {ECO:0000313|EMBL:KAF4124407.1};
OS Geosmithia morbida.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Bionectriaceae; Geosmithia.
OX NCBI_TaxID=1094350 {ECO:0000313|EMBL:KAF4124407.1, ECO:0000313|Proteomes:UP000749293};
RN [1] {ECO:0000313|EMBL:KAF4124407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=1262 {ECO:0000313|EMBL:KAF4124407.1};
RA Onufrak A., Murdoch R.W., Gazis R., Huff M., Staton M., Klingeman W.,
RA Hadziabdic D.;
RT "Site-based positive gene gene selection in Geosmithia morbida across the
RT United States reveals a broad range of putative effectors and factors for
RT local host and environmental adapation.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4124407.1}.
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DR EMBL; JAANYQ010000004; KAF4124407.1; -; Genomic_DNA.
DR RefSeq; XP_035323059.1; XM_035467047.1.
DR AlphaFoldDB; A0A9P4YXP0; -.
DR GeneID; 55971301; -.
DR OrthoDB; 10267235at2759; -.
DR Proteomes; UP000749293; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0004103; F:choline kinase activity; IEA:TreeGrafter.
DR GO; GO:0004305; F:ethanolamine kinase activity; IEA:TreeGrafter.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:TreeGrafter.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR Gene3D; 3.30.200.20; Phosphorylase Kinase, domain 1; 1.
DR InterPro; IPR007521; Choline_kin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF04428; Choline_kin_N; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KAF4124407.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000749293};
KW Transferase {ECO:0000313|EMBL:KAF4124407.1}.
FT DOMAIN 216..286
FT /note="Choline kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04428"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..131
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..631
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 84305 MW; 061242AB3B5BE00A CRC64;
MPTSGAASNG SGVAEQQQQQ HQPLRSALKN EDDADKALSA NGSSKAVQIS EPATESSFDD
DVSVRQFRAA HGRRLSGKPS PSLRPADEPG YPSREHSHRQ QYYGEKLLAQ VGEWLEWEKK
KISNRKKKSR PHPTSGSSQP HDPPPTSSDS TAPPRRPRSD SLDSQSSHIS LEKLQQILED
SMSSMGLGSA AHLSSKVSRS RRKRMGSLQR AASSDTDYHD GDAIVPDCDV WLDNSKTLAY
AAGTPSDTGD DDRSQRDYEA WVAFKNEILR AAHTLRLKGW RRVPLETGET MDVQRLSGAL
TNAVYVLTPP ADIPHQEGKP RPQKVLLRIY GPQVENLIDR ENELKVLQRL ARKKIGPRLL
GTFRNGRFEQ FFNASPLTPS DLRDPEVSRQ IAKRMRELHQ GIELLPQERE AGPCVWKNWD
QWLDNVGSIV PALDKQFEAA AADGSGQRRD SATSSWKANG YVCGVPWTQF KDVVHRYRAH
LDNYYKDRGG LNESLLFAHN DTQYGNILRF QPDDEKSPLL QPANKHKQLI VIDFEYAGAN
MLGQEFANHF TEWTYNYHDV KTPWACTPAG YPTLEEQRRF VKAYIEHRPH FHPTGGSTPR
LAPQDSNTTT PGAATPAQQP QPPQVQHTTS SSSIVDFMLD SRAPPGGWGA VEKAEEEKTE
KEIRQLLDET RMWRPANSAM WVAWGVVQAR IDEVTDDDDK DDGEAPTDEF DYLSYAQDRA
AFFWGDMVQM GLVKPEELPE SLRAKLKIVD H
//
