ID A0A9P5AFD8_9HYPO Unreviewed; 1060 AA.
AC A0A9P5AFD8;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=Ribosome assembly protein 1 {ECO:0000256|ARBA:ARBA00068031};
DE AltName: Full=Elongation factor-like 1 {ECO:0000256|ARBA:ARBA00081809};
GN ORFNames=FBEOM_8753 {ECO:0000313|EMBL:KAF4337369.1};
OS Fusarium beomiforme.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium burgessii species complex.
OX NCBI_TaxID=44412 {ECO:0000313|EMBL:KAF4337369.1, ECO:0000313|Proteomes:UP000730481};
RN [1] {ECO:0000313|EMBL:KAF4337369.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 25174 {ECO:0000313|EMBL:KAF4337369.1};
RX PubMed=29528269;
RA Laraba I., Keddad A., Boureghda H., Abdallah N., Vaughan M.M.,
RA Proctor R.H., Busman M., O'Donnell K.;
RT "Fusarium algeriense, sp. nov., a novel toxigenic crown rot pathogen of
RT durum wheat from Algeria is nested in the Fusarium burgessii species
RT complex.";
RL Mycologia 109:935-950(2017).
RN [2] {ECO:0000313|EMBL:KAF4337369.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 25174 {ECO:0000313|EMBL:KAF4337369.1};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + phosphate + H(+); Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00048548};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4337369.1}.
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DR EMBL; PVQB02000423; KAF4337369.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9P5AFD8; -.
DR OrthoDB; 364892at2759; -.
DR Proteomes; UP000730481; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0043022; F:ribosome binding; IEA:TreeGrafter.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0042256; P:cytosolic ribosome assembly; IEA:TreeGrafter.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR FunFam; 3.30.70.240:FF:000006; Elongation factor like GTPase 1; 1.
DR FunFam; 3.90.1430.10:FF:000002; Elongation factor like GTPase 1; 1.
DR FunFam; 3.40.50.300:FF:000746; Ribosome assembly protein 1; 1.
DR FunFam; 3.30.70.870:FF:000002; Translation elongation factor 2; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR056752; EFL1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF25118; EFL1; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:KAF4337369.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:KAF4337369.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000730481};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 17..325
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 1060 AA; 116804 MW; BC2DE0189BD1A88B CRC64;
MPVVTPDKLA SLQRQSSDIR NICILAHVDH GKTSLTDALL ATNGIISPKL AGKIRYLDSR
PDEQTRGITM ESSAISLYFA MRRKAAPDAE PEDKEYLVNL IDSPGHIDFS SEVSTASRLC
DGAVVLVDAV EGVCSQTVTV LRQTWTEKLK PLLVINKIDR LVTELKMTPG EAYIHLNKLL
EQVNAVLGSF FQGERMEEDL NWRERMEERV NAAAAAKESA IADQVSDTGD VQFEEKDDED
IYFAPEKNNV IFSSAIDGWA FTCRQFAAMY EKKLGIKRGI MEKILWGNFY LDPKTKKILG
PKHLKGRNLK PLFVQLVLEP VWTVYQATVG GDNGQGDREL LEKVTKSLGI KITPHMLKSR
DQKLLMTTIF ANWLPLSTAL LVSVIESLPS PPAAQAARLP EMIEESPGSE HIDQSIKAAM
VSFKHAKSDP VVAYVSKMVS VPESELPGNK RRAGAQMSGE EARELARKKR AEAARAQAAA
SENGVDSMAT SMDAINLDDF APELEEKKVD PEHLIGFARI YSGTLSVGDK LYVIPPKWSP
AEPDAASEPQ EVTVTALYML MGRNLEALES VPAGCVFGIG GLEGKILKSG TLCSRRNGAV
NLAGVTMLGK PIVRVALEPV NPADLDKMIH GLKLLVQSDP CAEYELLASG EHVLLTAGEL
HLERCLTDLK ERFALCDIQP GAPIVPYRET IVRAEEMRPP ANKELGRGAT VATTSSKQVT
LSLRVLPIPE NVTDFLVKNG DAVKRVYDRR AKKDDEDEEI IAEADVAAGN TLSVEDFKKQ
LKEKLETGKG RDIWKDCIDK IVAFGPRRTG PNLLIDSTTN GIFSKAFATE KVVETAPRAD
ESLHPSHLTD KISYAFQLAT AQGPLCNEPL QGVAVFVEDV TLNLAEDDSS ARDKLGRLTG
EVIRTFQSSL RAGFMDWSPR LMLAMYSVEI QASTEVLGRV YDVLTRRRGR VNAELMKEGT
PFFTIQALVP VAESFGFADE MRKRTSGAAQ PQLIFAGFEI LDEDPFWVPF TEDDLEDLGE
LADKENVAKR YMDGVRRKKG LLIEGRNVAT DAEKQKTLKR
//
