ID A0A9P5ASX3_9HYPO Unreviewed; 510 AA.
AC A0A9P5ASX3;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:KAF4344123.1};
GN ORFNames=FBEOM_1912 {ECO:0000313|EMBL:KAF4344123.1};
OS Fusarium beomiforme.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium burgessii species complex.
OX NCBI_TaxID=44412 {ECO:0000313|EMBL:KAF4344123.1, ECO:0000313|Proteomes:UP000730481};
RN [1] {ECO:0000313|EMBL:KAF4344123.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 25174 {ECO:0000313|EMBL:KAF4344123.1};
RX PubMed=29528269;
RA Laraba I., Keddad A., Boureghda H., Abdallah N., Vaughan M.M.,
RA Proctor R.H., Busman M., O'Donnell K.;
RT "Fusarium algeriense, sp. nov., a novel toxigenic crown rot pathogen of
RT durum wheat from Algeria is nested in the Fusarium burgessii species
RT complex.";
RL Mycologia 109:935-950(2017).
RN [2] {ECO:0000313|EMBL:KAF4344123.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 25174 {ECO:0000313|EMBL:KAF4344123.1};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF4344123.1}.
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DR EMBL; PVQB02000064; KAF4344123.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9P5ASX3; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000730481; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KAF4344123.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000730481};
KW Transferase {ECO:0000313|EMBL:KAF4344123.1}.
FT DOMAIN 125..264
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 510 AA; 55647 MW; 08EA6CDC298E752C CRC64;
MTMEIDRDME DGVGMLLLLE GKKKLIIGTK DLELNDPAAN KSSRSSCAPF SGKPSAKSTI
PFYNVLWAEL SNDQITIDYA DQVSKTLIKP RKWTFSLAKD DESTSGTPAE IFVKTLMTRA
YGDAQSQKRA YVLINPNSGP GGAVKQWENE VKPLFQAAKM QLDPVILKHG GEAVELAQNA
DLSKYDTIMA CSGDGTPHEI FNGLAKRPDA AKALATMPVS HIPCGSGNAF SCNLYGSHRP
SFAALAIIKG VVTPMDLVSV TTGHNRIISF LSQTLGLIAE CDLGTEHMRW MGSARFEVGV
VQRMFKKKCY PFDLAVKVEI EEKGDVKAHY KHHASSASLN HLAKKLDAGP AAEDAGLPPL
KYGTVQDDLP EGWELVPYNK VGTFYAGNMA YMSPDAPFFA ASLISDGLMD LVTIDGDLPF
FTAIKVLLDV EAERLFDNPH VTYKKISAYR IIPRDQEDGY ISIDGEKCPF GPLQAEIHQG
LGRVISKSGK YEAAGPKNWD KVTLADRIHG
//
