ID A0A9P7AYB4_9HELO Unreviewed; 518 AA.
AC A0A9P7AYB4;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE SubName: Full=Sphinganine kinase 5 {ECO:0000313|EMBL:KAG0649785.1};
GN ORFNames=D0Z07_3849 {ECO:0000313|EMBL:KAG0649785.1};
OS Hyphodiscus hymeniophilus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Hyphodiscaceae; Hyphodiscus.
OX NCBI_TaxID=353542 {ECO:0000313|EMBL:KAG0649785.1, ECO:0000313|Proteomes:UP000785200};
RN [1] {ECO:0000313|EMBL:KAG0649785.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 34498 {ECO:0000313|EMBL:KAG0649785.1};
RA Kramer G., Nodwell J.;
RT "Hyphodiscus hymeniophilus genome sequencing and assembly.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAG0649785.1}.
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DR EMBL; VNKQ01000007; KAG0649785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9P7AYB4; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000785200; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KAG0649785.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000785200};
KW Transferase {ECO:0000313|EMBL:KAG0649785.1}.
FT DOMAIN 139..278
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT REGION 343..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..359
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..378
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 57345 MW; BE427A647CF345EF CRC64;
MTTAAMATDN PFVDPIASFE EHGRDHSFAV DSTLPVGKNA SLTLGTDSLI VLDEAFEKRD
RTNCCGLWPS GTANTRAIPF YNILWAELQD DELRIDYASP ASKTVVRAAT LKYPFERQTL
EVVHKWIIKL LDRSYGESQR IKRMKVLVNP HSGKGSAEKW YHRDVEPLLI AARCTIDMQK
TKYSGEAVEI AEKMDIEAFD VVASCSGDGL PYEVFNGLAK RADAKKALTK IAVVNLPCGS
GNAMSWNLNG TDSNSLATLA VIKGIPTPLD LISITQGETR TLSFLSQSVG IVAESDLATE
NLRWMGGQRF TYGFLVRLWE KALYPCDIAI KVAIDDKPSI KEHYRREKSN HEPASERRGY
RNLLDDDASA SSGNDDGLPS LRYGTVNDKL PEGWELVPYD RLGNFYCGNM AYMAADSVFF
QAALPNDGYM DLVCINGDIP RTTAIKMMLG VENGNFFDMP GVWYRKVLGY RIIPKSKGDG
YISIDGERVP FQPFQAEVHK GLGTVLSKSG HMYEAPGL
//
