ID A0A9Q0NC04_9DIPT Unreviewed; 388 AA.
AC A0A9Q0NC04;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 9.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN Name=Rpn13 {ECO:0000313|EMBL:KAJ6647520.1};
GN ORFNames=Bhyg_02743 {ECO:0000313|EMBL:KAJ6647520.1};
OS Pseudolycoriella hygida.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Sciaroidea; Sciaridae;
OC Pseudolycoriella.
OX NCBI_TaxID=35572 {ECO:0000313|EMBL:KAJ6647520.1, ECO:0000313|Proteomes:UP001151699};
RN [1] {ECO:0000313|EMBL:KAJ6647520.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HSMRA1968 {ECO:0000313|EMBL:KAJ6647520.1};
RC TISSUE=Whole embryos {ECO:0000313|EMBL:KAJ6647520.1};
RA Trinca V., Uliana J.V.C., Torres T.T., Ward R.J., Monesi N.;
RL Submitted (JUL-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ6647520.1}.
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DR EMBL; WJQU01000001; KAJ6647520.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9Q0NC04; -.
DR OrthoDB; 340431at2759; -.
DR Proteomes; UP001151699; Chromosome A.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|EMBL:KAJ6647520.1};
KW Reference proteome {ECO:0000313|Proteomes:UP001151699}.
FT DOMAIN 16..129
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 258..370
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 173..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..209
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 42296 MW; 809CA546BFD58F13 CRC64;
MSGPIFGNNS SMGSSGGNRH LVEFRAGRMN MVGKMVTPDT RKGLVYLFQA EDQLIHFCWK
DRSTGKVEDD LIIFPDDCEF KRIDQCKTGR VYLLKFKSSS KRLFFWMQEP KNDKDDEYCR
RMNDIMNNPP SANSLSSSRV GESNDLQNML NNMSQMQLMQ LFGGVGQMGG LSNLLGSIHR
PSDSSRTSAR TSTTSTTPAS ATATATTAPE TPNNAVSVVT PTAPKKNDSG KKDDVSKVLL
SELQSFLSGL KTSDGSGPSS TNGRNIDLST AVNAETVSFL TDAERTENLL AHLPNIESND
NTKQQLRETI SSPQFQQALS MFSSALQSGQ LGPVVSQFQL NDEAVAAATT GDLEQFVKAL
EKNAKEIVAK ASEKDKEQDK KEDKSGST
//
