ID A0A9R1WTQ7_LACSA Unreviewed; 422 AA.
AC A0A9R1WTQ7;
DT 13-SEP-2023, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN ORFNames=LSAT_V11C100007430 {ECO:0000313|EMBL:KAJ0228626.1};
OS Lactuca sativa (Garden lettuce).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae;
OC Lactucinae; Lactuca.
OX NCBI_TaxID=4236 {ECO:0000313|EMBL:KAJ0228626.1, ECO:0000313|Proteomes:UP000235145};
RN [1] {ECO:0000313|EMBL:KAJ0228626.1, ECO:0000313|Proteomes:UP000235145}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Salinas {ECO:0000313|Proteomes:UP000235145};
RC TISSUE=Seedlings {ECO:0000313|EMBL:KAJ0228626.1};
RX PubMed=28401891; DOI=10.1038/ncomms14953;
RA Reyes-Chin-Wo S., Wang Z., Yang X., Kozik A., Arikit S., Song C., Xia L.,
RA Froenicke L., Lavelle D.O., Truco M.J., Xia R., Zhu S., Xu C., Xu H.,
RA Xu X., Cox K., Korf I., Meyers B.C., Michelmore R.W.;
RT "Genome assembly with in vitro proximity ligation data and whole-genome
RT triplication in lettuce.";
RL Nat. Commun. 8:14953-14953(2017).
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ0228626.1}.
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DR EMBL; NBSK02000001; KAJ0228626.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9R1WTQ7; -.
DR Gramene; rna-gnl|WGS:NBSK|LSAT_1X17041_mrna; cds-PLY82937.1; gene-LSAT_1X17041.
DR OrthoDB; 760019at2759; -.
DR Proteomes; UP000235145; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd11393; bHLH_AtbHLH_like; 1.
DR FunFam; 4.10.280.10:FF:000032; Transcription factor bHLH123 family; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR045239; bHLH95_bHLH.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR045843; IND-like.
DR PANTHER; PTHR16223:SF171; BASIC HELIX-LOOP-HELIX (BHLH) DNA-BINDING SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR16223; TRANSCRIPTION FACTOR BHLH83-RELATED; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000235145};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 307..356
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 371..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 47090 MW; 8D3DF53F951F7CE5 CRC64;
MESTNFHHQQ QQEHHQPLVD SSCYGLAWYQ NPILNGTRIS TNSRDVKQHI NHSIDLVPPP
TVQDLGLPLS TMESFMAHEL QHLARIKEEV SLSRSYPGLS EMIISSSPTS SIEDLHLHPS
PTYMSKNDHQ RIRYDNDNNQ EIFLKTFSNG CQIKSDHQHM NQIPFSEESV SYSDDTNSCY
RGTFSQILPT INISSLNQSS STPPLAISSS SFDINLPALD PFRSPTFDGS FRYQPSSLNI
HNLGGLLKDN CLSYGLDQMH QPNHSQAVCH SKVSPPFIIE TTEAKRSASN YMDAKAIKAT
PPKKSKLELR PSCAPLKVRK EKLGDRISAL QQMVAPFGKT DTASVLMEAI GYIKFLQNQV
ETLSVPYMNS TQKATRTSTR GGSIKNGNEE MKRDLRSRGL CLVPLSCLSY VTYGGGNIWA
TP
//
