ID A0A9W3H934_CAMBA Unreviewed; 120 AA.
AC A0A9W3H934;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE SubName: Full=Protein Mdm4 isoform X7 {ECO:0000313|RefSeq:XP_045362683.1};
DE SubName: Full=Protein Mdm4 isoform X8 {ECO:0000313|RefSeq:XP_045362683.1};
GN Name=MDM4 {ECO:0000313|RefSeq:XP_045362683.1};
OS Camelus bactrianus (Bactrian camel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=9837 {ECO:0000313|Proteomes:UP001732780, ECO:0000313|RefSeq:XP_045362683.1};
RN [1] {ECO:0000313|RefSeq:XP_045362683.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_045362683.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MDM2/MDM4 family.
CC {ECO:0000256|ARBA:ARBA00005803}.
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DR RefSeq; XP_045362683.1; XM_045506727.1.
DR RefSeq; XP_045362683.1; XM_045506727.2.
DR AlphaFoldDB; A0A9W3H934; -.
DR GeneID; 105080248; -.
DR CTD; 4194; -.
DR Proteomes; UP001732780; Chromosome 23.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0002039; F:p53 binding; IEA:TreeGrafter.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:TreeGrafter.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:TreeGrafter.
DR CDD; cd17673; MDM4; 1.
DR FunFam; 1.10.245.10:FF:000002; E3 ubiquitin-protein ligase Mdm2; 1.
DR Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR InterPro; IPR016495; p53_neg-reg_MDM_2/4.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR46858; OS05G0521000 PROTEIN; 1.
DR PANTHER; PTHR46858:SF12; PROTEIN MDM4; 1.
DR Pfam; PF02201; SWIB; 1.
DR PIRSF; PIRSF006748; p53_MDM_2/4; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP001732780};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 25..108
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
SQ SEQUENCE 120 AA; 13383 MW; B71D79AAE9434608 CRC64;
MTSFSTSAQC STSDSACRIS PEQTNQVRPK LPLLKILQAA GAQGEMFTVK EVMHYLGQYI
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTGNVYRN
//
