ID A0A9W6SQY3_9ACTN Unreviewed; 272 AA.
AC A0A9W6SQY3;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 18-JUN-2025, entry version 6.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000256|HAMAP-Rule:MF_00187,
GN ECO:0000313|EMBL:GLZ80488.1};
GN ORFNames=Afil01_52950 {ECO:0000313|EMBL:GLZ80488.1};
OS Actinorhabdospora filicis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinorhabdospora.
OX NCBI_TaxID=1785913 {ECO:0000313|EMBL:GLZ80488.1, ECO:0000313|Proteomes:UP001165079};
RN [1] {ECO:0000313|EMBL:GLZ80488.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 111898 {ECO:0000313|EMBL:GLZ80488.1};
RA Ichikawa N., Sato H., Tonouchi N.;
RT "Actinorhabdospora filicis NBRC 111898.";
RL Submitted (MAR-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC Rule:MF_00187}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GLZ80488.1}.
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DR EMBL; BSTX01000004; GLZ80488.1; -; Genomic_DNA.
DR RefSeq; WP_285665670.1; NZ_BSTX01000004.1.
DR Proteomes; UP001165079; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.10; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR NCBIfam; TIGR00129; fdhD_narQ; 1.
DR NCBIfam; NF001943; PRK00724.1-2; 1.
DR PANTHER; PTHR30592; FORMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30592:SF1; SULFUR CARRIER PROTEIN FDHD; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00187};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|HAMAP-Rule:MF_00187};
KW Reference proteome {ECO:0000313|Proteomes:UP001165079}.
FT ACT_SITE 108
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
SQ SEQUENCE 272 AA; 28631 MW; E34425CB68B54338 CRC64;
MGRVTDRRRV ERINEGGRSF RPDTLIVEEP LEIQINGEPL TVTMRTPGDD VDLALGWLYA
EGIISSYEDV ITAKHCTDSD LNVLDVRLAP HVPVPDRAGR GFTVSSACGA CGTSSLEALR
EVTAKAVRWR IGDDDVEVGV DLLAALPDRL RASQRAFART GGVHAAGLFD ASGTEVAVRE
DVGRHNAVDK IVGGRLRDGG VPLTGHVLMA SGRVGYEIVQ KAAMAGIPVL AAVSAPSTLA
VDLAADLGMT LVGFVRGSSM NVYSGSARVS SS
//
