ID A0A9W8IKS9_9FUNG Unreviewed; 925 AA.
AC A0A9W8IKS9;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 28-JAN-2026, entry version 10.
DE SubName: Full=Cdc7p-Dbf4p kinase complex regulatory subunit {ECO:0000313|EMBL:KAJ2866171.1};
GN Name=DBF4 {ECO:0000313|EMBL:KAJ2866171.1};
GN ORFNames=GGH94_001702 {ECO:0000313|EMBL:KAJ2866171.1};
OS Coemansia aciculifera.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=417176 {ECO:0000313|EMBL:KAJ2866171.1, ECO:0000313|Proteomes:UP001140074};
RN [1] {ECO:0000313|EMBL:KAJ2866171.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RSA 476 {ECO:0000313|EMBL:KAJ2866171.1};
RA Reynolds N.K., Stajich J.E., Barry K., Grigoriev I.V., Crous P.,
RA Smith M.E.;
RT "Phylogenomic reconstructions and comparative analyses of Kickxellomycotina
RT fungi.";
RL Submitted (JUL-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ2866171.1}.
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DR EMBL; JANBUY010000043; KAJ2866171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9W8IKS9; -.
DR Proteomes; UP001140074; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001140074};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 563..612
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 99978 MW; FC0B427A61878412 CRC64;
MASRKLTFDA PKPSARNLGA SPAARTAMYA TSQNHGITSP ERALATPTRP AQRATLTRLQ
QTRRSMVGLT SPGQLTPVHH PTASLGRRNP LQAITEKEKQ RGNQQALTPA TPDAHSATVT
TLGLTTPHAK MPTQTQLNDS AVASAVAVAE QQRVQKARVA EWVFAYRRAF PSFVFYFEGI
DEGTVQRLTA PIRGLGASVE TFFSAQTVTH VIVESAEVAN DANSDSGSHV VSLAKRFQLK
IWDLEKLEKR VLAILLPGYN AANAQGGASV MSAKRKLNEA FSTEKLYAMR HKAFEGTSVA
HCVDFYYFKY FYVLVEDATH LNRPAIVEDY RPPEPGRDPP WPKLYMVPTG RCPFLQYEDP
TTSSKGSDSD ADDNKENVTP EPEATLPTTQ LLSKTPASRL QTPHRKAWTP TAQHPTNELS
HCAAKPFATV QGSRARADAT REAADYLLTP TRPSRAMVNE LGPPKAIRPM DASLMMDSNA
SGIARSHGVT STSTAFHPSA ADPTLQQSLL QNLNGGRVTH LSKLEQPVVG PRVAGATNAV
RRSGRVPPTP RTMKPRVAVR RPVVAMPGFC ENCHLKYDDM IEHIKTPQHR RFATNERNWI
ELDSLLARVQ RPVLRQQVTS MDDSRHHALY ALSSDDACMS APANVSSAAP GPANSAETSV
VASAPAALAS NWTGRLFAGR QFGPSYPSPH ILASGRFSAE TTDRTTMASG QSMPCTTGTP
TTACAVDLTF PESNSPCASH AGDLSVDYIA LPDELEMGPK TGSTVHSVDM PFTPVPRRGV
AASTSIESLV SSLETPRFCN DSLKGHYDDG ATLFGDGTGR LRQQQAVLFE TPTRPGNQGA
LNVVGRDSIS ARYNAAASRM RPSSSSFDAC SPTSIGGATL VQPSRIKSKF AEYDENTVPG
TTGDKHESTE EHHLNRALHG QVQQM
//
