ID A0A9W8LF53_9FUNG Unreviewed; 837 AA.
AC A0A9W8LF53;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 28-JAN-2026, entry version 10.
DE SubName: Full=Cdc7p-Dbf4p kinase complex regulatory subunit {ECO:0000313|EMBL:KAJ2777930.1};
GN Name=DBF4 {ECO:0000313|EMBL:KAJ2777930.1};
GN ORFNames=H4R18_004890 {ECO:0000313|EMBL:KAJ2777930.1};
OS Coemansia javaensis.
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=2761396 {ECO:0000313|EMBL:KAJ2777930.1, ECO:0000313|Proteomes:UP001140217};
RN [1] {ECO:0000313|EMBL:KAJ2777930.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 105414 {ECO:0000313|EMBL:KAJ2777930.1};
RA Reynolds N.K., Stajich J.E., Barry K., Grigoriev I.V., Crous P.,
RA Smith M.E.;
RT "Phylogenomic reconstructions and comparative analyses of Kickxellomycotina
RT fungi.";
RL Submitted (JUL-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ2777930.1}.
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DR EMBL; JANBUL010000259; KAJ2777930.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A9W8LF53; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP001140217; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001140217};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 527..576
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 728..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..394
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..422
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..509
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..702
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..777
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 88859 MW; 172C9D158D40F529 CRC64;
MASRRLTFDA SRPSARHPGA SPADRTMLRT SNAHHLDLAS PTPTRALGTP TRMLAGTPTR
VALATPTRPG QRAGPTRMAP AGSPAHTLAA HAMTTPVRAR AAADAGPAYS PAAPARAGRG
PLHVIAANRE PPATAPRAAA ALQREQQQRE QRARVAEWIY AYRQAFPSFV FYFEGIGDAA
AQRLSAPIRS LGAKIETFFS AQTVTHVIVE HADAGGSHVV ELARRFQLKI WDVTKLEKRV
LAMLLPGYSA GAGPGAGDGV LSAKRKLSEA FSAERLYAMR HKTFEGASVA HCVEFHYFNY
VYVLVEDATH LHRPAILADF HPPEPGRDPP WPKLYMVPTG RCPFVQYEDP TTSSKGSDTD
DANGGGGNKE NVTPEPEPTL PTAPLPSKTP ASRLRTPRRR GLWPPPPPLQ PLPLRPLPPP
AANAPACGLG PLPPPPIDSN ASGIAQSNAV TSTSTAFSLA ALDPVMQRSL LQNLNGGRVT
RLSRLEQPAP GSAHAAAASP AAARAHGGRA PPPPRTRKPR APVRRPAVAR PGYCENCRVK
YDDQAEHVRS PQHCRFADDA ASWADLDALL ARVQRPLRDP QPLPHPPAAA PHPAACALSS
DNASQAASCA SLDASWICPP STQPASYPAL TSAHHRSAAS DALDVALPLR CAAPVARPAA
TIVDLAYSTA SASCTSPHDA RDHAAFPADD APSSNNNDND NSNIEDLVAS LETPRFRSTA
ASVVDADATI ANDDDARRKR ARHSFAQQQQ QQQQQQQQFT TPTRPRTHAA AATAPATPLA
SLDALQRLSG QTLVQPSRTK RLAHVRDEND APADGGKLPA TSRHSLPHAL RGGSDVL
//
