ID A0A9W9TGD1_PENCI Unreviewed; 631 AA.
AC A0A9W9TGD1;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=N7469_010276 {ECO:0000313|EMBL:KAJ5221389.1};
OS Penicillium citrinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5077 {ECO:0000313|EMBL:KAJ5221389.1, ECO:0000313|Proteomes:UP001147733};
RN [1] {ECO:0000313|EMBL:KAJ5221389.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 23319 {ECO:0000313|EMBL:KAJ5221389.1};
RA Petersen C.;
RL Submitted (NOV-2022) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAJ5221389.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 23319 {ECO:0000313|EMBL:KAJ5221389.1};
RX PubMed=36726175;
RA Petersen C., Sorensen T., Nielsen M.R., Sondergaard T.E., Sorensen J.L.,
RA Fitzpatrick D.A., Frisvad J.C., Nielsen K.L.;
RT "Comparative genomic study of the Penicillium genus elucidates a diverse
RT pangenome and 15 lateral gene transfer events.";
RL IMA Fungus 14:0-0(2023).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ5221389.1}.
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DR EMBL; JAPQKT010000009; KAJ5221389.1; -; Genomic_DNA.
DR RefSeq; XP_056496312.1; XM_056649181.1.
DR AlphaFoldDB; A0A9W9TGD1; -.
DR GeneID; 81388348; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP001147733; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001147733};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 575..624
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..71
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70858 MW; A043942FEDDFFAAB CRC64;
MSTRRPLANV PNATNSPHRA GLLPGKRARS TQMEIPYGQP PPKKQVMDSV EHESRSPSRS
RSTLQQSTES RLFARRSNNA NPSAFEKKLV AARDRERQPT VKATKGEKPS ADTLDNIRQW
QRHYRKAFPQ FVFYFDTIPE DVRRKFSRQV VALGAREEKF FSRLVTHVVT SRPIPAETVT
SPTEEANPAT EANGDANVQT VNPSLLDKSA GRRDQGNMDV LQRARQMGMK IWALEKLQRM
ITTINDNDLG GQHDAVSRGK TAGGNATHGK GDNDLSRVLR QELLNGPSDR DPLSSMEMLV
FKGPFIYIHD MNEKTKPVMV REYSRVARRQ DGVWPQFRSA PLGKCPFIDE PPSRKELDRH
RMRQAQKEKK AGRKNTEETQ LQPPAAHENT VETKVSTELA KPQKSVEEPT RPPTQAEFPA
KPSFDETRER KSSESLIPPH FPRTGPFYTG REPAASGVQP SNVTSAIRSQ MISSTAAAPG
AKAGLSKEVH GLKRKVLEKG TGTVVTGSMA APQRPGNGSS LNPARAQSTE SNKSAAPEKN
GQHEEDGNQS EGGGAKRRRD ERRDSQPKKT EQRRRDPKPG YCENCRDKFD DFEEHTLTRK
HRRFAQNSSN WAELDALLFE IQRPLKEEYE F
//
