ID A0A9W9VSA1_9EURO Unreviewed; 634 AA.
AC A0A9W9VSA1;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 28-JAN-2026, entry version 11.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=N7509_010781 {ECO:0000313|EMBL:KAJ5388240.1};
OS Penicillium cosmopolitanum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1131564 {ECO:0000313|EMBL:KAJ5388240.1, ECO:0000313|Proteomes:UP001147747};
RN [1] {ECO:0000313|EMBL:KAJ5388240.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 29677 {ECO:0000313|EMBL:KAJ5388240.1};
RA Petersen C.;
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAJ5388240.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 29677 {ECO:0000313|EMBL:KAJ5388240.1};
RX PubMed=36726175;
RA Petersen C., Sorensen T., Nielsen M.R., Sondergaard T.E., Sorensen J.L.,
RA Fitzpatrick D.A., Frisvad J.C., Nielsen K.L.;
RT "Comparative genomic study of the Penicillium genus elucidates a diverse
RT pangenome and 15 lateral gene transfer events.";
RL IMA Fungus 14:0-0(2023).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ5388240.1}.
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DR EMBL; JAPZBU010000009; KAJ5388240.1; -; Genomic_DNA.
DR RefSeq; XP_056486038.1; XM_056635418.1.
DR AlphaFoldDB; A0A9W9VSA1; -.
DR GeneID; 81374398; -.
DR OrthoDB; 21380at2759; -.
DR Proteomes; UP001147747; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001147747};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 578..627
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..208
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..585
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 71952 MW; 785B1753231BFD85 CRC64;
MAAVFVPPSP QTSLNMSTRR PLANVPNATN SPHRTGLLPA KRARSTQIEI PYGQPPPKKQ
VMDVAEQETR SPSRSRSTLQ QSTESRLFAR RSNNANPSAF EKKLVAARDR ERQPVVKGTK
GERPSADTLD NIRQWQRHYR KAFPQFVFYF DSIPEDVRQK FSRQVVALGA REEKFFSRLV
THVVTSRPIP AEAVTSPTEE STATPEASGD AHVQTVNPSL LDKSAGRRDQ GSMDVLQRAR
QMGMKIWALE KLQRMITTIN DNELAGQHDA VSRSKAAGGH ASHGKGDNDL SRVLRQEMLN
GPSDRDPLAS MEMLVFKGPF IYIHDMNEKT KPVMVREYSR VAKRQDGSWP QFRSAPLGKC
PFIDEPPSRK EYDRHRMRQA QKEKKATRQN VEEPQPQPAP TNETPVDTKT STEASKPQTS
IEEHFKPSTQ VEIPAKPSFE ESHERKSSES FIPPHFPRTG PFYTGREPAA SGVQPSNVTS
AIRSQMISST AAAPGAKAGL SKEIHGLKRK VLEKGDWWYH HWINGRASTS QQWISNKSAV
PEKTGQEEDG NQSEGVGNKR RRDERRDNQQ KKPEQRRRDP KPGYCENCRD KFDDFEEHTL
TRKHRRFAQN TSNWAELDAL LFEIQRPLKD EYQF
//
