ID A0A9X1YL04_9PROT Unreviewed; 309 AA.
AC A0A9X1YL04;
DT 08-NOV-2023, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 1.
DT 02-APR-2025, entry version 7.
DE SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:MCK8787921.1};
GN ORFNames=M0638_26555 {ECO:0000313|EMBL:MCK8787921.1};
OS Roseomonas acroporae.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Acetobacterales; Roseomonadaceae; Roseomonas.
OX NCBI_TaxID=2937791 {ECO:0000313|EMBL:MCK8787921.1, ECO:0000313|Proteomes:UP001139516};
RN [1] {ECO:0000313|EMBL:MCK8787921.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NAR14 {ECO:0000313|EMBL:MCK8787921.1};
RA Sun H.;
RT "Roseomonas acroporae sp. nov., isolated from coral Acropora digitifera.";
RL Submitted (APR-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MCK8787921.1}.
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DR EMBL; JALPRX010000157; MCK8787921.1; -; Genomic_DNA.
DR RefSeq; WP_248669967.1; NZ_JALPRX010000157.1.
DR Proteomes; UP001139516; Unassembled WGS sequence.
DR GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IEA:TreeGrafter.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF19; 5-DEHYDRO-4-DEOXYGLUCARATE DEHYDRATASE 2-RELATED; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP001139516}.
FT ACT_SITE 143
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 167
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 55
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 309 AA; 32327 MW; E8824223AC06B112 CRC64;
MIQPGSALRA ALNGISGILV TPFDAQDRPV PYRLAPIVDR AVRAGVHILV ANGNTSEFYG
LTTAEAEAMV HGAAEVVAGR VPLVAGVGRG IGDACALARA SRKAGAAALM VHQPPDPFVA
PRGVVAYVRR VAEAAEGLPI VLYLRNDGIG LDAIEALCNI PEVVGVKWAS PTPLRLGECI
RRTAGRDIAW VGGLAETWAP PLYAVGARGF TSGLINVWPE HSVAIHAALE AGDYGRAAAL
IETMEPFEAL RAEEGNGTNV TVVKASLQLM GEDCGPTRPP SAWPLTPRAD AELRRNLAAW
GLTRHAAAE
//
