ID A0AA35TGI1_GEOBA Unreviewed; 403 AA.
AC A0AA35TGI1;
DT 24-JAN-2024, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE SubName: Full=Proteasomal ubiquitin receptor ADRM1 {ECO:0000313|EMBL:CAI8046536.1};
GN ORFNames=GBAR_LOCUS25747 {ECO:0000313|EMBL:CAI8046536.1};
OS Geodia barretti (Barrett's horny sponge).
OC Eukaryota; Metazoa; Porifera; Demospongiae; Heteroscleromorpha;
OC Tetractinellida; Astrophorina; Geodiidae; Geodia.
OX NCBI_TaxID=519541 {ECO:0000313|EMBL:CAI8046536.1, ECO:0000313|Proteomes:UP001174909};
RN [1] {ECO:0000313|EMBL:CAI8046536.1}
RP NUCLEOTIDE SEQUENCE.
RA Steffen K., Cardenas P.;
RL Submitted (MAR-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAI8046536.1}.
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DR EMBL; CASHTH010003569; CAI8046536.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AA35TGI1; -.
DR Proteomes; UP001174909; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|EMBL:CAI8046536.1};
KW Reference proteome {ECO:0000313|Proteomes:UP001174909}.
FT DOMAIN 12..118
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 242..348
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 115..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..218
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..354
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 41956 MW; 1F8C2B08297494FD CRC64;
MALFGGTVDE RREPRSLVEF RAGKMSLSQG VVTADKRKGL VYMKTSGDSL LHFCWKDRQN
GEVVDAEFLT IPQCTTGRVF LLKFKDHSSR RFFYWMQEPS SSKDKELAKK VNELLTNPPE
GGGGEGLPDL PPGYMAIPSS QLQSMLSGGR VDQQQLMELL GGAAGGIPHA LAGGGLGRAG
GVSADRPSSQ VSHTPTSSAL PAATPRAPSR PTRSQQQQLD DLQSILSSLN VPGETQAAES
QQSSPEDAVN LNEVFSSHVI RPLANDEEVV AELSSHLPPT GETAEDVLSS PQFQSALSTF
HSGLTSGQLG PLMSQFGLGD GVSQSAASGD LKAFADALQG EMGGGGASGG GGVASGTTGE
EGEGEKGEGG EGEGKKEGGG KKEGEGKKEG EGEKEEQKGS EQN
//
