ID A0AA37Q785_9BACT Unreviewed; 283 AA.
AC A0AA37Q785;
DT 24-JAN-2024, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2024, sequence version 1.
DT 18-JUN-2025, entry version 7.
DE RecName: Full=Sulfur carrier protein FdhD {ECO:0000256|HAMAP-Rule:MF_00187};
GN Name=fdhD {ECO:0000256|HAMAP-Rule:MF_00187,
GN ECO:0000313|EMBL:GLC24286.1};
GN ORFNames=rosag_07990 {ECO:0000313|EMBL:GLC24286.1};
OS Roseisolibacter agri.
OC Bacteria; Pseudomonadati; Gemmatimonadota; Gemmatimonadia;
OC Gemmatimonadales; Gemmatimonadaceae; Roseisolibacter.
OX NCBI_TaxID=2014610 {ECO:0000313|EMBL:GLC24286.1, ECO:0000313|Proteomes:UP001161325};
RN [1] {ECO:0000313|EMBL:GLC24286.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AW1220 {ECO:0000313|EMBL:GLC24286.1};
RA Tobiishi Y., Tonouchi A.;
RT "Draft genome sequencing of Roseisolibacter agri AW1220.";
RL Submitted (AUG-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formate dehydrogenase (FDH) activity. Acts as a
CC sulfur carrier protein that transfers sulfur from IscS to the
CC molybdenum cofactor prior to its insertion into FDH.
CC {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00187}.
CC -!- SIMILARITY: Belongs to the FdhD family. {ECO:0000256|HAMAP-
CC Rule:MF_00187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GLC24286.1}.
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DR EMBL; BRXS01000001; GLC24286.1; -; Genomic_DNA.
DR RefSeq; WP_284348734.1; NZ_BRXS01000001.1.
DR Proteomes; UP001161325; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0097163; F:sulfur carrier activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.10; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR HAMAP; MF_00187; FdhD; 1.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR003786; FdhD.
DR NCBIfam; TIGR00129; fdhD_narQ; 1.
DR NCBIfam; NF001943; PRK00724.1-2; 1.
DR PANTHER; PTHR30592; FORMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR30592:SF1; SULFUR CARRIER PROTEIN FDHD; 1.
DR Pfam; PF02634; FdhD-NarQ; 1.
DR PIRSF; PIRSF015626; FdhD; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00187};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150,
KW ECO:0000256|HAMAP-Rule:MF_00187};
KW Reference proteome {ECO:0000313|Proteomes:UP001161325}.
FT ACT_SITE 123
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
FT BINDING 265..270
FT /ligand="Mo-bis(molybdopterin guanine dinucleotide)"
FT /ligand_id="ChEBI:CHEBI:60539"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00187"
SQ SEQUENCE 283 AA; 29897 MW; 4858166DB9F94563 CRC64;
MRVADAGAAP GVARHEVRRV EGAREARADD DLLAVEEPLL IELAHDRDGG RVTDSVAVTM
RTPGHDVELA LGFLWAEGIL ADADELLRAP EALDANTVRV TLRTGVPVDL RRLERHFHTT
SSCGVCGKTS LEALAAARPI ALPAAHPIVD ATTIHALPDA LRAAQDVFAS TGGLHAAALF
TPDGRLRCVR EDVGRHNAVD KLVGRLLLDG ALPMHDGVLL VSGRASFELV HKALAAGIPV
LAAVGAPSSL AVETARAYDA TLVGFVRQQR FNVYAGAARI RTE
//
