ID A0AA38I6P4_9CUCU Unreviewed; 405 AA.
AC A0AA38I6P4;
DT 24-JAN-2024, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2024, sequence version 1.
DT 28-JAN-2026, entry version 10.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN ORFNames=Zmor_021640 {ECO:0000313|EMBL:KAJ3649924.1};
OS Zophobas morio.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Zophobas.
OX NCBI_TaxID=2755281 {ECO:0000313|EMBL:KAJ3649924.1, ECO:0000313|Proteomes:UP001168821};
RN [1] {ECO:0000313|EMBL:KAJ3649924.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=QUZm001 {ECO:0000313|EMBL:KAJ3649924.1};
RX PubMed=37002914; DOI=10.1093/g3journal/jkad079;
RA Kaur S., Stinson S.A., diCenzo G.C.;
RT "Whole genome assemblies of Zophobas morio and Tenebrio molitor.";
RL G3 (Bethesda) 13:jkad079-jkad079(2023).
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ3649924.1}.
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DR EMBL; JALNTZ010000006; KAJ3649924.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AA38I6P4; -.
DR Proteomes; UP001168821; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP001168821}.
FT DOMAIN 19..132
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 272..382
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..235
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..405
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 43255 MW; 084E9D022FFE8237 CRC64;
MPAGGALFGS AATGPGSTGG NKHLVEVRAG KMNLKGRMVY PDKRKGLLYV YQSDDSLMHF
CWQDRTTGIV EDDLIIFPDD CEYIKVPQCT TGRVYLLKFK SSSRKFFFWL QEPRTDKDDD
NCKRINELLN NPSSAVQSSQ SPDQDLQSLF NNMSQSQLMQ LFGSGVGQMG GLSSLLGTIR
GPNSGSARTS TTPAITHRTT VPSTPTTNTT TTTVSSNPPA TTTTPQTTTA PVTAPGAPAR
ASNTARSSDS SCGHRIQLSD LQNFLQGITP ISSSQQSGVD LSTALTADSL SGILNNPGAL
QALQSHLPAV EGDPQEALRS TINSPQFQQA VSQFSSALES GQLGPVVSQL AVNPEAVAAA
AQGNMQDFVK ALEKNEATGS KEESDKDKKE EKKDDKDDDQ NMQLD
//
