ID A0AA38MXV2_9AGAR Unreviewed; 565 AA.
AC A0AA38MXV2;
DT 24-JAN-2024, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2024, sequence version 1.
DT 28-JAN-2026, entry version 9.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=DFJ43DRAFT_594619 {ECO:0000313|EMBL:KAJ3724991.1};
OS Lentinula guzmanii.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Omphalotaceae; Lentinula.
OX NCBI_TaxID=2804957 {ECO:0000313|EMBL:KAJ3724991.1, ECO:0000313|Proteomes:UP001176059};
RN [1] {ECO:0000313|EMBL:KAJ3724991.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ET3784 {ECO:0000313|EMBL:KAJ3724991.1};
RG DOE Joint Genome Institute;
RA Min B., Sierra-Patev S., Naranjo-Ortiz M., Looney B., Konkel Z., Slot J.C.,
RA Sakamoto Y., Steenwyk J.L., Rokas A., Carro J., Camarero S., Ferreira P.,
RA Molpeceres G., Ruiz-duenas F.J., Serrano A., Henrissat B., Drula E.,
RA Hughes K.W., Mata J.L., Ishikawa N.K., Vargas-Isla R., Ushijima S.,
RA Smith C.A., Ahrendt S., Andreopoulos W., He G., LaButti K., Lipzen A.,
RA Ng V., Riley R., Sandor L., Barry K., Martinez A.T., Xiao Y., Gibbons J.G.,
RA Terashima K., Hibbett D.S., Grigoriev I.V.;
RL Submitted (AUG-2022) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAJ3724991.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ET3784 {ECO:0000313|EMBL:KAJ3724991.1};
RX PubMed=36848567;
RA Sierra-Patev S., Min B., Naranjo-Ortiz M., Looney B., Konkel Z., Slot J.C.,
RA Sakamoto Y., Steenwyk J.L., Rokas A., Carro J., Camarero S., Ferreira P.,
RA Molpeceres G., Ruiz-Duenas F.J., Serrano A., Henrissat B., Drula E.,
RA Hughes K.W., Mata J.L., Ishikawa N.K., Vargas-Isla R., Ushijima S.,
RA Smith C.A., Donoghue J., Ahrendt S., Andreopoulos W., He G., LaButti K.,
RA Lipzen A., Ng V., Riley R., Sandor L., Barry K., Martinez A.T., Xiao Y.,
RA Gibbons J.G., Terashima K., Grigoriev I.V., Hibbett D.;
RT "A global phylogenomic analysis of the shiitake genus Lentinula.";
RL Proc. Natl. Acad. Sci. U.S.A. 120:0-0(2023).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ3724991.1}.
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DR EMBL; JANVFO010000048; KAJ3724991.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AA38MXV2; -.
DR Proteomes; UP001176059; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001176059};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 476..525
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 64082 MW; DE40C497FE03957C CRC64;
MATTARNPLS QRSRPSLASP RVPKQSLGLK RPRSPGVAPE DLLSNGAPKR AKAAPEALHE
KQRRKEQQES EWREKYVRAF STFKFHFSED IQNTDYAKHL EKRVLQLGAT VEDFFSSSIT
HLIVKDIEQG RASDKENRSG HRSPTKKVGL IPEVPQVYRR IVDEAKIREW GVRKLDSVLS
RCLLQPVILP TSGPLPSRLN LMTTIHSTSR SRSLNKLLQS ERIHGTTERD PTQKRHDFIY
FARGSYFVLA EDIHQELATI VAHQYIPPKK GSTRTPWPVL HCHPQSRGPF VPFDEKERNR
WEKAQKMERE EKLEAHHQEL KEQKLFQERI TREREALHRG FDLRRSVSMN NLRRRESLEV
EAANDQYLDL GDPDSACASG YLASGNGGYI AASGNSVSVT STTGTTSTAG SNFGLGSKLS
AKLKAFADQQ VPTSLKSRRN SIKGDMGPPA VPEGRVGVGL RRAKSTNNLK LPKREEGSKP
GYCESCRQKF EDFKQHIRGS KHRKFAKEDA HFAELDIVLA TVKRKTVDEI TQERDARYFH
EEVAEDDPFL DDLDSRMPDV DLDDI
//
