ID A0AA39M011_9BILA Unreviewed; 415 AA.
AC A0AA39M011;
DT 24-JAN-2024, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2024, sequence version 1.
DT 28-JAN-2026, entry version 9.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN ORFNames=QR680_012025 {ECO:0000313|EMBL:KAK0415610.1};
OS Steinernema hermaphroditum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=289476 {ECO:0000313|EMBL:KAK0415610.1, ECO:0000313|Proteomes:UP001175271};
RN [1] {ECO:0000313|EMBL:KAK0415610.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PS9179 {ECO:0000313|EMBL:KAK0415610.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:KAK0415610.1};
RA Schwarz E.M., Heppert J.K., Baniya A., Schwartz H.T., Tan C.-H.,
RA Antoshechkin I., Sternberg P.W., Goodrich-Blair H., Dillman A.R.;
RT "Genomic analysis of the entomopathogenic nematode Steinernema
RT hermaphroditum.";
RL Submitted (JUN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK0415610.1}.
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DR EMBL; JAUCMV010000002; KAK0415610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AA39M011; -.
DR Proteomes; UP001175271; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP001175271}.
FT DOMAIN 13..132
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 252..362
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 126..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..155
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 43999 MW; DD58935BA9E83404 CRC64;
MALFANASRG GVSNSSHLVE FKAGRSTLEE GSTPEKRKVV SDKTKGLVYI KQSSDQLVHF
IWKNRETNTI VDDLIIFPGD TEFLKVKECT DGRVFMLKFN SNSDRRLFWM QDNKADKDDE
LVKKVNDLLN RPPSSRASGR GGTTERSGGL AASLSALGNG SEDMGALNSL DQNQLMQLLQ
LMNTNGTSGS SADALISSAL GGSADGATGT PATGAAAAEA GAGTGSVKLS DLQAILSQID
GKSTEGGAAV AGTSRGPQAA LTDVLKSSNV SEIVKTNEQR LIPHLPNEAP IKADKNELNM
TISTPQFQQA ASIFGTALQT GQMGPVLQQF GCSENVRAAA ATGDLLQFAK KLTEDERGEP
IKEDEAKPTA DVEMTSAEVD AQINREAEAE ETTESAIKEP DAKRNKTTDD NMELD
//
