ID A0AA87YWX9_FICCA Unreviewed; 1408 AA.
AC A0AA87YWX9;
DT 27-MAR-2024, integrated into UniProtKB/TrEMBL.
DT 27-MAR-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51192};
GN ORFNames=TIFTF001_000296 {ECO:0000313|EMBL:GMN23882.1};
OS Ficus carica (Common fig).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Ficeae; Ficus.
OX NCBI_TaxID=3494 {ECO:0000313|EMBL:GMN23882.1, ECO:0000313|Proteomes:UP001187192};
RN [1] {ECO:0000313|EMBL:GMN23882.1}
RP NUCLEOTIDE SEQUENCE.
RA Takahashi T., Nishimura K.;
RT "draft genome sequence of fig (Ficus carica).";
RL Submitted (JUL-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GMN23882.1}.
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DR EMBL; BTGU01000001; GMN23882.1; -; Genomic_DNA.
DR Proteomes; UP001187192; Unassembled WGS sequence.
DR GO; GO:0055087; C:Ski complex; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IEA:TreeGrafter.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR FunFam; 3.40.50.300:FF:000354; ATP-dependent RNA helicase SKI2; 1.
DR FunFam; 1.10.3380.30:FF:000010; DExH-box ATP-dependent RNA helicase DExH11; 1.
DR FunFam; 1.10.3380.30:FF:000001; Ski2 ATP-dependent RNA helicase; 1.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR025696; Beta-barrel_MTR4.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR050699; RNA-DNA_Helicase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF24; DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH11; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP001187192};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 380..535
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 282..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..633
FT /note="Gly residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1408 AA; 158161 MW; 207C49E4DEC177D0 CRC64;
MEPIKAANEL QFRVGFSGHS GHLRLQPLSS VERSDPLNSL PDFVLPPAFP TETPESIKSY
IEETFLSPRL DSELFSPEKA GRQWDFDWFD KANVPLEPSL PRSVVIPTWE LPFRRQKKRS
VQGNWELSSV QVNVSEITVG AQESGSLPRM NGTAKDFVRG SLNNRPFRPG GLDDSQSVQR
IPDGVTNGEW VHELLSGGPS QAIPPGFKQG LDLGDLKAYP CTWRVYKDQS SPDSTSEKKP
NELSVQFDDL FKKAWEEDVT EFMEDEKESV KSEPEAGCMM LEEAESSKSE PEAESIKSEA
KSEQIDVPND ASSSELSTLD EILLVEAAES TSNDGGGEHQ KEARAVTGGS EWISRHFYEL
IPDMALDFPF ELDAFQKEAI YYLERGESVF VAAHTSAGKT VVAEYAFALA SKHCTRAVYT
APIKTISNQK YRDFCGKFDV GLLTGDVSLR PEASCLIMTT EILRSMLYRG ADIIRDIEWV
IFDEVHYVND VERGVVWEEV IIMLPRHINI VLLSATVPNT VEFADWIGRT KQKQIRVTGT
TKRPVPLEHC IFYPGELYKV CENEIFMPQG VKVAKDAFKK KNVISSGTGS HGRGSAAYDS
SRGQKRENFA RGKQNKHFGS QGSGNFPGSG GGNQNNGYGL NNWGLKRSDA SLWLSLINKL
SKKSLLPVVI FCFSKNRCDK SADKMTGTDL TSSSEKSEIR IFCDKAFSRL KGSDRNLPQV
VRVQSLLRRG IGVHHAGLLP IVKEVVEMLF CRGVIKVLFS TETFAMGVNA PARTVQFYFA
FDRLQTLIEK LIKHAFLQLR PVAGVESLFE FYLLQVVFDT LRKFDGKEFR QLLPGEYTQM
AGRAGRRGLD KIGTVVIMCR DEIPKESDLK RVIVGSATKL ESQFRLTYIM ILHLLRVEEL
KVEDMLKRSF AEFHAQKKLP ETQQLLMRKL AQPTKAIECI KCEPDIEEYY EMYSEAEKYN
REVLEAVMQT SAAQKLLNPG RVVVVKSQSQ AQYHMLGVVV KAPSTNNKQH IVLVLKPELP
ALETPLVGGK LQDSRSGDQQ QGYYVMPKSK RGLDEEYYSP ATSRKGSGVI KIKLPYSGVA
AGTAYEVRGI DNNEFLCICN CKIRIESVQL LEDASTFAYS KTVQQLLEKK SDGNKYPPAL
DPVKDLQLKD VDHVETYYKW TNLLQKMAKN KCHGCIKLEQ HITLVKEIKK HKEEVNILRY
QMSDEALQQM PDFQGRIDVL KEIGCVDADL VVQIKGRVAC EMNSGEELIC TECLFENQLD
DLEPEEAVAL MSAFVFQQRN ASEPSLTPKL SQAKQRLYDT AIRLGKLQAE FKVQINPEEY
ARENLKFGLV EVVYEWAKGT PFADICELTD VPEGMIVRTI VRLDETCREF KNAAAIMGNS
ALYKKMETAS NAIKRDIVFA ASLYVTGV
//
