ID A0AA97MPQ3_9PASS Unreviewed; 1330 AA.
AC A0AA97MPQ3;
DT 27-MAR-2024, integrated into UniProtKB/TrEMBL.
DT 27-MAR-2024, sequence version 1.
DT 08-OCT-2025, entry version 8.
DE SubName: Full=COFA1 protein {ECO:0000313|EMBL:NXE96279.1};
DE Flags: Fragment;
GN Name=Col15a1_1 {ECO:0000313|EMBL:NXE96279.1};
GN ORFNames=MENNOV_R07190 {ECO:0000313|EMBL:NXE96279.1};
OS Menura novaehollandiae (superb lyrebird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
OC Passeriformes; Menuridae; Menura.
OX NCBI_TaxID=47692 {ECO:0000313|EMBL:NXE96279.1};
RN [1] {ECO:0000313|EMBL:NXE96279.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B10K-CU-030-46 {ECO:0000313|EMBL:NXE96279.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:NXE96279.1};
RA Zhang G.;
RT "Bird 10,000 Genomes (B10K) Project - Family phase.";
RL Submitted (DEC-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- SIMILARITY: Belongs to the multiplexin collagen family.
CC {ECO:0000256|ARBA:ARBA00061275}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:NXE96279.1}.
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DR EMBL; VWPS01000369; NXE96279.1; -; Genomic_DNA.
DR Proteomes; UP000521578; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0031012; C:extracellular matrix; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR CDD; cd00247; Endostatin-like; 1.
DR FunFam; 3.10.100.10:FF:000008; collagen alpha-1(XVIII) chain isoform X1; 1.
DR FunFam; 3.40.1620.70:FF:000003; Collagen type XVIII alpha 1; 1.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023:SF1112; COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydroxylation {ECO:0000256|ARBA:ARBA00023278};
KW Proteoglycan {ECO:0000256|ARBA:ARBA00022974};
KW Reference proteome {ECO:0000313|Proteomes:UP000521578};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 8..196
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT DOMAIN 57..195
FT /note="Laminin G"
FT /evidence="ECO:0000259|SMART:SM00282"
FT REGION 198..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1021..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..566
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..669
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..735
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..795
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1051
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1061..1070
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:NXE96279.1"
FT NON_TER 1330
FT /evidence="ECO:0000313|EMBL:NXE96279.1"
SQ SEQUENCE 1330 AA; 139538 MW; 14A4541ACCF6161D CRC64;
AERGSKGHLD LTELIGVPLP PSVYFVTGYG GFPAYSFGPD SNIGRLTSAI IPSPFYRDFA
IVVTVKPNSD RGGVLFAITD AFQKTIYLGL RISPVDDSTQ RIIMYYTEPG SHISREAASF
KVPVMTNRWN RFTVTVQGND VALFMDCEEY QRLQFQRSAR TLAFESGSGI FVGNAGATGL
EKFTGSIQHL TIKFDPRATE DHCEDDDPYA SGDSSGNGSI QEHEVSEAQE ALAPSHLPQR
PEDTLAEPVE APPTILSYLE ENYFSGNHRS EETSEAAKFK EQGTTWGAAV IETGQGNRES
TSVTQKILRE EDGSGAGVLP GVSGVLYNGF ITSQIFFFHL CLVLLLPRCR IWHLFSFSFM
LLITAQCFNL SRSLCKASCS SRLPAAPPSL LLANANLLML LSTPASRSLR HILNRTGPRI
ESQETPLGTG YQPDVALFTA SLELCPSDSS SSKNLRRSFQ TTVTICSNGT LRFSKYFVIS
AVVVQLAHCR VQMQPAKCPP KQPSLPLYCG KSRCGERHIL DTASCIEVQN PVSPPTAQTK
NYNLAPLDPA SAAKCPPGLP GLPGKPAPDS GVGPPGSPGE DGASGGPGPE YNLQGPQGPP
GHDGVVGPRG WKGEKGDQGL PGSAGPKGDT GVTGSIGPKG EAGPVGSPGK PGPPGPPGPP
GSPGPPGPPG LSYSLGSELE KTHFIIFPFK SLMLFFFYHL QGPKGEKGDP GHQGEPGQDG
SSIVGPPGPP GPPGPVIAIP ELLLNDTDGI FNVTEIKGLL GPPGADGKPG LPGFPGPRGP
KGDTGLPGSQ GPKGQQGEKG EPGAIIAADG SLTGLLGRKG EKGEAGVVGP AGPMGPIGPT
GPKGELGFPG RPGRPGLNGL RGVKGDRGEA FNGLPGLPGP PGPPGPPGRI LYIKGTVFPV
PPRPRCKTPV STPYPGNQEV FNDHGAKANR DSWGLHSLAH LKGEKGDRGA PGPPGPPLPP
SYFSHFINSI KGEKGDNGVT GVKGEKGEPN GGVLLTGPPG PPGRPGLVGP KGDSVVGPRG
PSGLPGLPGL PGYGKIGLPG PPGPPGPPGP PAIHGSAAAM PGPPGPPGEP GSPATRNLVT
TFQNIEGMLE KVHYVAEGTL IYLRETSEVF IRVQNGWRKL QLGELIPIPA DSLPPPAISS
HGFQSIPVLR SISNMNNGKP ALHLVALNFP FSGDMRADFQ CFQQAQLAGL TSTYRAFLSS
HLQDLATVVR KTDRYHLPIV NLQGETLFSN WESIFDGNGG QFNIHVPIYS FDGRNVMTDS
SWPQKVIWHG STANGIRLVS NYCEAWHTAD MGAMGQASPL KTGKLLDQKV YSCNNQFIVL
CIENSFVSDP
//
