ID A0AAD3RFF2_LATJO Unreviewed; 589 AA.
AC A0AAD3RFF2;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE SubName: Full=Mast/stem cell growth factor receptor kita-like protein {ECO:0000313|EMBL:GLD66391.1};
DE Flags: Fragment;
GN ORFNames=AKAME5_001778500 {ECO:0000313|EMBL:GLD66391.1};
OS Lates japonicus (Japanese lates).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangaria incertae sedis; Centropomidae; Lates.
OX NCBI_TaxID=270547 {ECO:0000313|EMBL:GLD66391.1, ECO:0000313|Proteomes:UP001279410};
RN [1] {ECO:0000313|EMBL:GLD66391.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Kochi {ECO:0000313|EMBL:GLD66391.1};
RA Hashiguchi Y., Takahashi H.;
RT "Genome sequencing of akame (Lates japonicus).";
RL Submitted (AUG-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GLD66391.1}.
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DR EMBL; BRZM01000092; GLD66391.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD3RFF2; -.
DR Proteomes; UP001279410; Unassembled WGS sequence.
DR GO; GO:0005911; C:cell-cell junction; IEA:TreeGrafter.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0050839; F:cell adhesion molecule binding; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:TreeGrafter.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 3.30.200.20; Phosphorylase Kinase, domain 1; 1.
DR InterPro; IPR051275; Cell_adhesion_signaling.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF31; IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF25305; Ig_PDGFR_d4; 1.
DR PIRSF; PIRSF000615; TyrPK_CSF1-R; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Magnesium {ECO:0000256|PIRSR:PIRSR000615-3};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000615-3};
KW Receptor {ECO:0000313|EMBL:GLD66391.1};
KW Reference proteome {ECO:0000313|Proteomes:UP001279410};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..589
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5042195209"
FT TRANSMEM 519..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..94
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 210..306
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT BINDING 566
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR000615-3"
FT NON_TER 589
FT /evidence="ECO:0000313|EMBL:GLD66391.1"
SQ SEQUENCE 589 AA; 66434 MW; 6A6292D6822B0D3F CRC64;
MRCHWVVFAS HFLLLPLTVW CEPIISPRGP HVVVPKRGKL ELRCHDNATT PSAPSGLRWQ
RERARRLEGE VEEGGVVYVR VPSVQAFHMG RYVCVNNSTL EHSSIYVYVK DSQNAFQRTM
VNVILVRAGE NCTIPCLVTD PEVTLLALET CDGRPLPFGM SYHSNLQRGI IISNVRKEHE
GCYVCVGQLG GLKVTSTQYT VDVRLVPAVP PVITLSHKDR VILRKGEKFE LTCSSTNVNP
DFSLKWDFPS AVHPNESQTS HILSGSRGYE RSTTLLITAV NQSDSGTYRC YAHNERGTSA
IALQLNIFDQ GFITMLGSPG PVQADVKEGE SLSLRVEFDA YPSPRSLFWS YNGKRLLNTT
EHVITVHRRK YRYISELRLV RVLGSEGGIY KFSASHEDAS VDHSFHVYVN SKPVIIAQEG
PVDGQVRCIA AGYPVPKISW YFCELPHTRC SHLPNATQLE NPEVAMVTES AFGRSEVESR
LNVSKEHAHY HTLECVASTE GEEAYTLFSI SERIVPHKLF TPLLTGMVAT GILLSLILVV
LLYKYMQKPK FQIQWKVIES IHGNNYIYID PTQLPYDSKW EFPRQKLRF
//
