ID A0AAD4M5Q0_9AGAM Unreviewed; 477 AA.
AC A0AAD4M5Q0;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 5.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAI0302340.1};
GN ORFNames=B0F90DRAFT_1714063 {ECO:0000313|EMBL:KAI0302340.1};
OS Multifurca ochricompacta.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Russulales; Russulaceae; Multifurca.
OX NCBI_TaxID=376703 {ECO:0000313|EMBL:KAI0302340.1, ECO:0000313|Proteomes:UP001203297};
RN [1] {ECO:0000313|EMBL:KAI0302340.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BPL690 {ECO:0000313|EMBL:KAI0302340.1};
RX PubMed=34861049;
RA Looney B., Miyauchi S., Morin E., Drula E., Courty P.E., Kohler A., Kuo A.,
RA LaButti K., Pangilinan J., Lipzen A., Riley R., Andreopoulos W., He G.,
RA Johnson J., Nolan M., Tritt A., Barry K.W., Grigoriev I.V., Nagy L.G.,
RA Hibbett D., Henrissat B., Matheny P.B., Labbe J., Martin F.M.;
RT "Evolutionary transition to the ectomycorrhizal habit in the genomes of a
RT hyperdiverse lineage of mushroom-forming fungi.";
RL New Phytol. 233:2294-2309(2022).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAI0302340.1}.
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DR EMBL; WTXG01000011; KAI0302340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD4M5Q0; -.
DR Proteomes; UP001203297; Unassembled WGS sequence.
DR GO; GO:0004460; F:L-lactate dehydrogenase (cytochrome) activity; IEA:TreeGrafter.
DR GO; GO:0006089; P:lactate metabolic process; IEA:TreeGrafter.
DR CDD; cd02922; FCB2_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 2.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR000262; FMN-dep_DH.
DR InterPro; IPR037396; FMN_HAD.
DR InterPro; IPR008259; FMN_hydac_DH_AS.
DR InterPro; IPR037458; L-MDH/L-LDH_FMN-bd.
DR PANTHER; PTHR10578:SF148; L-LACTATE DEHYDROGENASE (CYTOCHROME); 1.
DR PANTHER; PTHR10578; S -2-HYDROXY-ACID OXIDASE-RELATED; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF01070; FMN_dh; 2.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
DR PROSITE; PS00557; FMN_HYDROXY_ACID_DH_1; 1.
DR PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP001203297}.
FT DOMAIN 2..76
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT DOMAIN 102..443
FT /note="FMN hydroxy acid dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51349"
SQ SEQUENCE 477 AA; 53391 MW; 7F99C51C992ACDB4 CRC64;
MTKPISGKIV AQHNSRDSCW IIVHGKVYDV TEFLDGGSKI ILKYAGKDAT QEYEPIHPPS
AIIDNLPPER HLGPVEEGTV EKVEVRITDE EKARLQRVEA RPPLSEILNL HDFEAIGRLT
MPEKAWAYYS SASDDEITNR ENHAAFHRIW FRPRILRDVT NVDWSTTIIG HASTMPIYIS
ATALGKLGHP EGELNLTRAA AKHGIIQMIP TLSSCSFDEI VDAAQPDQVQ FFQLYVNKDR
AITKRIDMRM AFDAEDPHEI GKSGSDKVDR SRGAAKAITG FIDPGLKWAD ISWFKSITRM
PLILKGVQTW EDALEAYDQN LAGIVLSNHG GRQLDFARSG IEVLVEVVEK FKEKRGITFP
NDRFQLLVDG GVRRATDVLK AIALGATAVG IGRPFLYAFS TYGVDGVDHA LQILQDEFEM
NLRLLGAGTI KDVVPDMVDV SNIRSHLVTV PRDRLYDINY ESMQHARLRD TKAKTKL
//
