ID A0AAD5PH49_9FUNG Unreviewed; 569 AA.
AC A0AAD5PH49;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=BDA99DRAFT_556995 {ECO:0000313|EMBL:KAI9271782.1};
OS Phascolomyces articulosus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Lichtheimiaceae; Phascolomyces.
OX NCBI_TaxID=60185 {ECO:0000313|EMBL:KAI9271782.1, ECO:0000313|Proteomes:UP001209540};
RN [1] {ECO:0000313|EMBL:KAI9271782.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RSA 2281 {ECO:0000313|EMBL:KAI9271782.1};
RX PubMed=35996588;
RA Chang Y., Wang Y., Mondo S., Ahrendt S., Andreopoulos W., Barry K.,
RA Beard J., Benny G.L., Blankenship S., Bonito G., Cuomo C., Desiro A.,
RA Gervers K.A., Hundley H., Kuo A., LaButti K., Lang B.F., Lipzen A.,
RA O'Donnell K., Pangilinan J., Reynolds N., Sandor L., Smith M.E., Tsang A.,
RA Grigoriev I.V., Stajich J.E., Spatafora J.W.;
RT "Evolution of zygomycete secretomes and the origins of terrestrial fungal
RT ecologies.";
RL IScience 25:0-0(2022).
RN [2] {ECO:0000313|EMBL:KAI9271782.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RSA 2281 {ECO:0000313|EMBL:KAI9271782.1};
RG DOE Joint Genome Institute;
RA Mondo S.J., Chang Y., Wang Y., Ahrendt S., Andreopoulos W., Barry K.,
RA Beard J., Benny G.L., Blankenship S., Bonito G., Cuomo C., Desiro A.,
RA Gervers K.A., Hundley H., Kuo A., LaButti K., Lang B.F., Lipzen A.,
RA O'Donnell K., Pangilinan J., Reynolds N., Sandor L., Smith M.W., Tsang A.,
RA Grigoriev I.V., Stajich J.E., Spatafora J.W.;
RL Submitted (FEB-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAI9271782.1}.
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DR EMBL; JAIXMP010000006; KAI9271782.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD5PH49; -.
DR Proteomes; UP001209540; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001209540};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 492..541
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 32..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..52
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..268
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 63929 MW; 64A20B0C78A76DF3 CRC64;
MNQTIIGKPH TTNVATTIAT KTAITNENIP LATKENNNEN ASPPNNNTNG GETPEELKKQ
FSQFKFYLDN IDDQQQKKIR DRLKIFLATV EPFFSKKCTH VVTTRPIPKK LTALNENKHV
DDTISIALKW NLKIWSLDHM NRVMQSMVYG HSSGHRANRT KAIGKLLEDE KKYGVGTNHG
GSTNARNITK QVRPMFVPFQ KYYLSVEDTR GVYRPVAVKE YEPGRPYPYP KITPGGKSPF
ISLPHHHVLP PLPPRTPSTP KSSSQPLPSE KEEQKQPTKE IIDKENDRPS SQQTLPNKPH
PTFAKPLEPS KATTMIPNPV STPPMSPIDQ SMQQQQQHPN NLHDNINNIN NNIQYSSSHL
KASGLYPSQS TNAFSRTTRA TLTNSRIIST TSESTTKLYM DNAQPHDERV AQLDRRMVDN
NRASHGSNNN GSLRTEGAAS GGAGGNIHPN TGGVGAGNSK QLLKTAAMNQ TAKEKEKLRQ
EQEKTQAQKK KEQDLMHWCE NCNKRYINLK EHLEEKAHQT FVQDVNNFSK FDELVATIRR
PKLQQQQPSN ATSSKDVPLK NENDMDIDP
//
