ID A0AAD6IKI8_PENCN Unreviewed; 651 AA.
AC A0AAD6IKI8;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=N7460_002811 {ECO:0000313|EMBL:KAJ6052277.1};
OS Penicillium canescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5083 {ECO:0000313|EMBL:KAJ6052277.1, ECO:0000313|Proteomes:UP001219568};
RN [1] {ECO:0000313|EMBL:KAJ6052277.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 15450 {ECO:0000313|EMBL:KAJ6052277.1};
RX PubMed=36726175;
RA Petersen C., Sorensen T., Nielsen M.R., Sondergaard T.E., Sorensen J.L.,
RA Fitzpatrick D.A., Frisvad J.C., Nielsen K.L.;
RT "Comparative genomic study of the Penicillium genus elucidates a diverse
RT pangenome and 15 lateral gene transfer events.";
RL IMA Fungus 14:0-0(2023).
RN [2] {ECO:0000313|EMBL:KAJ6052277.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 15450 {ECO:0000313|EMBL:KAJ6052277.1};
RA Petersen C.;
RL Submitted (JAN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ6052277.1}.
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DR EMBL; JAQJZL010000002; KAJ6052277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD6IKI8; -.
DR Proteomes; UP001219568; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001219568};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 593..642
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..206
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 73246 MW; 4219246C8111303B CRC64;
MATVFVPPSP RTSLTMATRR PLANVPNATN SPHRSGPVPA KRSRSTQMEI PYGQPPPKKQ
VMEAIENDGR SPSRSRSATA QNTDSKLFAR RSNNATPSAF EKKLVAAREK ERQPLVKTIK
TEKASADTMD TIRQWQRHYR KAFPQFVFYF DSIPEDVRRK FSRQVIALGA REEKFFSRLV
THVVTSRAIP PESTSPTEAE TTADATNGDG NVQTVNPSML ERNGDTHLHV SLKTDTRRDQ
GTMDVLQRAR QMGMKIWALE KLQRMITTIN DSDIGAQADT ASRSKTAGGN AANGKGENDL
SRVLRQELLN GPSDRDPLSS MEMLMFKGPF VYIHDMNEKT KPVMVREYSR VARRQDGSWP
QFRSAPLGKC PFIDEPPSRK EYDRHRLRQL QKEKKAALHN TDGNREAKPK ATAPAHRVQD
TKLVTEVTKS KPSEHEQRIP PAIQTESQKP SFDENNERKS SESFIPPHFP RTGPFYTGRE
PAASGVQPSN MTSAIRSQMI SSTAAAPGAK AGLSKEVHGL KRKVLEKGTG AIGAGSMAAP
QRREGSVPVQ CKNMNPPGRS NLRHEDDGNQ SEVAGSKRQR EDKEQQRKSE RRRDPKPGYC
ENCRDKFDDF EEHTLTRKHR RFAANSTNWA ELDALLFEIQ RPLKDKYEYD E
//
