ID A0AAD6MTI3_9EURO Unreviewed; 639 AA.
AC A0AAD6MTI3;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=DBF4-type domain-containing protein {ECO:0000259|PROSITE:PS51265};
GN ORFNames=N7493_008068 {ECO:0000313|EMBL:KAJ5716157.1};
OS Penicillium malachiteum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1324776 {ECO:0000313|EMBL:KAJ5716157.1, ECO:0000313|Proteomes:UP001215712};
RN [1] {ECO:0000313|EMBL:KAJ5716157.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 17514 {ECO:0000313|EMBL:KAJ5716157.1};
RX PubMed=36726175;
RA Petersen C., Sorensen T., Nielsen M.R., Sondergaard T.E., Sorensen J.L.,
RA Fitzpatrick D.A., Frisvad J.C., Nielsen K.L.;
RT "Comparative genomic study of the Penicillium genus elucidates a diverse
RT pangenome and 15 lateral gene transfer events.";
RL IMA Fungus 14:0-0(2023).
RN [2] {ECO:0000313|EMBL:KAJ5716157.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IBT 17514 {ECO:0000313|EMBL:KAJ5716157.1};
RA Petersen C.;
RL Submitted (JAN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAJ5716157.1}.
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DR EMBL; JAQJAN010000012; KAJ5716157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD6MTI3; -.
DR Proteomes; UP001215712; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR CDD; cd00027; BRCT; 1.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001215712};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 581..630
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..428
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..447
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 72288 MW; CD490F578D49B932 CRC64;
MAAVLISQSP QTSLNMSTRR PLANVPNATN SPHRTVTLPA KRVRSNQLEI PYGQPPPKKQ
VMEAAEQESR SPRSRSTVSQ STESRLFAFE KKLVAARDKE RQSLAKGTKG EKPSADTLDT
IRQWQRHYRK AFPSFVFYFD SIPEDVRRKF SRQVIALGAR EETFFSRCVT HVVTSRPIPE
IPSTNHTELD QSTVDGPNRD VNVQTVNPSL LERNADSQRH VSLKPDGRRD QGNMDVLQRA
RQMGMKIWAL EKLQRMITTI NDNGYLGNQN EAASRSKATG GNTTNGRGEN DLSRVLRQEL
LNGPSDRDPF SSMEMIIFKG PFIYIHDMNE KTKPVMVREY SRVANRQEGK WPQFRSAPLG
KCPFIDEPPS RKDQDRQRQK QAQKEKEAKL ADESRLKVSQ SAVSRSVETK VQTEDSQADR
GQDEKSTSKT DISTKPLIDE THERKSSESF IPTHFPRTGP FYTGREPAAS GVQPSNVTSA
IRSQMISSTA AAPGAKAGLS KEVHGLKRKV LEKGTGAISN GSMAAPQNPT IGKMALYRGT
TDTRRVMEAR RADKENSNPS EAAGTKRRRD SQELEQKKPR RDPKPGYCEN CRDKFDDFEE
HTMTRMHRRF AQNMSNWAEL DALLFELRRP LKEEYDDEE
//
