ID A0AAD8FE69_BIOPF Unreviewed; 397 AA.
AC A0AAD8FE69;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 6.
DE SubName: Full=Proteasomal ubiquitin receptor ADRM1 {ECO:0000313|EMBL:KAK0060543.1};
GN ORFNames=Bpfe_010056 {ECO:0000313|EMBL:KAK0060543.1};
OS Biomphalaria pfeifferi (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=112525 {ECO:0000313|EMBL:KAK0060543.1, ECO:0000313|Proteomes:UP001233172};
RN [1] {ECO:0000313|EMBL:KAK0060543.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KasaAsao {ECO:0000313|EMBL:KAK0060543.1};
RX PubMed=36961841;
RA Bu L., Lu L., Laidemitt M.R., Zhang S.M., Mutuku M., Mkoji G.,
RA Steinauer M., Loker E.S.;
RT "A genome sequence for Biomphalaria pfeifferi, the major vector snail for
RT the human-infecting parasite Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 17:0-0(2023).
RN [2] {ECO:0000313|EMBL:KAK0060543.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KasaAsao {ECO:0000313|EMBL:KAK0060543.1};
RC TISSUE=Whole Snail {ECO:0000313|EMBL:KAK0060543.1};
RA Bu L., Lu L., Laidemitt M.R., Zhang S.M., Mutuku M., Mkoji G.,
RA Steinauer M., Loker E.S.;
RL Submitted (APR-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK0060543.1}.
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DR EMBL; JASAOG010000035; KAK0060543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD8FE69; -.
DR Proteomes; UP001233172; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|EMBL:KAK0060543.1};
KW Reference proteome {ECO:0000313|Proteomes:UP001233172}.
FT DOMAIN 13..126
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 278..391
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 114..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 42224 MW; 8B841CFF4F4D9698 CRC64;
MAALFGNTAS SRNQSKNLVE FRAGKMHMKG KMVHPDKRKG LIYVYQSDDS LMHFCWKDRS
SGVVEDDLII FPDDIEFQHV SQCTTGRVYV LKFKSSSRKF FFWLQEPKAD KDEDNCKKVN
DFLNNPPTPG SSRGSGGHGL PSDLSSLGDQ DLQSILGGMS QQQLMQLLGG IGMGGGSGSN
VLGSLMGRPS SAQSIVSEPP LRTQSSAGAR ATSGESTPPP PRPVTAAALP SQPTSGDASR
SINNSLGATS VSATTAAGAS AQIQLSDLQN ILSTMKVPSD GAGKEVDLAK ALSPEAMIPI
LANSEVQKRL IPYLPEGESL PKTEEELRNT VQSPQFQQAL SSFSSALQSG QLGPLMSQFG
LGEDVANAAA QGDMEAFVKA MQEAGKKKEK DNDSMEH
//
