ID A0AAD9T7Z5_EUCGR Unreviewed; 683 AA.
AC A0AAD9T7Z5;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
DE Flags: Fragment;
GN ORFNames=EUGRSUZ_L03326 {ECO:0000313|EMBL:KAK2631149.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KAK2631149.1, ECO:0000313|Proteomes:UP000030711};
RN [1] {ECO:0000313|EMBL:KAK2631149.1, ECO:0000313|Proteomes:UP000030711}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BRASUZ1 {ECO:0000313|Proteomes:UP000030711};
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KAK2631149.1};
RX PubMed=24919147; DOI=10.1038/nature13308;
RA Myburg A.A., Grattapaglia D., Tuskan G.A., Hellsten U., Hayes R.D.,
RA Grimwood J., Jenkins J., Lindquist E., Tice H., Bauer D., Goodstein D.M.,
RA Dubchak I., Poliakov A., Mizrachi E., Kullan A.R., Hussey S.G., Pinard D.,
RA van der Merwe K., Singh P., van Jaarsveld I., Silva-Junior O.B.,
RA Togawa R.C., Pappas M.R., Faria D.A., Sansaloni C.P., Petroli C.D.,
RA Yang X., Ranjan P., Tschaplinski T.J., Ye C.Y., Li T., Sterck L.,
RA Vanneste K., Murat F., Soler M., Clemente H.S., Saidi N., Cassan-Wang H.,
RA Dunand C., Hefer C.A., Bornberg-Bauer E., Kersting A.R., Vining K.,
RA Amarasinghe V., Ranik M., Naithani S., Elser J., Boyd A.E., Liston A.,
RA Spatafora J.W., Dharmwardhana P., Raja R., Sullivan C., Romanel E.,
RA Alves-Ferreira M., Kulheim C., Foley W., Carocha V., Paiva J., Kudrna D.,
RA Brommonschenkel S.H., Pasquali G., Byrne M., Rigault P., Tibbits J.,
RA Spokevicius A., Jones R.C., Steane D.A., Vaillancourt R.E., Potts B.M.,
RA Joubert F., Barry K., Pappas G.J., Strauss S.H., Jaiswal P.,
RA Grima-Pettenati J., Salse J., Van de Peer Y., Rokhsar D.S., Schmutz J.;
RT "The genome of Eucalyptus grandis.";
RL Nature 510:356-362(2014).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK2631149.1}.
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DR EMBL; MU850825; KAK2631149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAD9T7Z5; -.
DR Proteomes; UP000030711; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IEA:UniProtKB-ARBA.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR FunFam; 1.50.10.20:FF:000011; Terpene cyclase/mutase family member; 1.
DR FunFam; 1.50.10.20:FF:000064; Uncharacterized protein; 1.
DR Gene3D; 1.50.10.20; -; 3.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000030711};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 99..358
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 378..680
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
FT NON_TER 683
FT /evidence="ECO:0000313|EMBL:KAK2631149.1"
SQ SEQUENCE 683 AA; 78122 MW; BC21B8D27EA922F3 CRC64;
MWKLKIAEGE DDPYLYSTNN YVGRQTWEFD PKAGNAEERA EVEATCQHFY DHRHQVKACG
DLLWRMQFLR EKQFKQTISP VRVEDGEEIT YDKASTALRR TVHFFSALQA SDGHWPAEIA
GPLYFLPPLV MCVYITGHLN AVFPAEHRKE ILHYLYNHQN GDGGWGFHIE GHSTMFCTAL
SYICMRILGE GPDGGQDNAC TRARKWILDR GGVTYIPSWG KTWLSIFGLF DWSGTNPMPP
EFWILPSFLP MHPAKMWCYC RMVYMPMSYL YGKRFVGPIT PLVQQLREEL HTQPYDTICW
RKVCHLCAKE DLYYPHPLVQ DLIWDSLYIF AEPLLNRWPF NKLREKALQV TMKHIHYEDE
NSRYITIGCV EKSFGSQEWD TGFAIQALLA SNMTEEIAPV LARGHDFIKK SQVKDNPSGD
FKSMHRHITK GSWTFSDQDH GWQVSDCTAE GLRCCLLFSM MPPEIVGEKM EPEKLYDAVN
ILLSLQSKNG GLPAWEPAGA PAWLELLNPT EFFEDIVIEH EYVECTSSAI QALVLLRKLY
PGHRKKEIAD FISNSVKYLE NVQKPDGSWY GCWGVCFTYG SWFALGGLAA AGKTYSNCAA
MREGVAFLLR TQLQDGGWGE SYLSCPKKEY VPLEGNRSNL VQTAWAMMGL IHAGQAERDP
TPLHRAAKLL INSQMEDGDY PQQ
//
