ID A0AAE0RDT8_9TELE Unreviewed; 683 AA.
AC A0AAE0RDT8;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=Forkhead box protein G1 {ECO:0000256|ARBA:ARBA00034868};
GN ORFNames=QTP70_013992 {ECO:0000313|EMBL:KAK3551139.1};
OS Hemibagrus guttatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Bagridae; Hemibagrus.
OX NCBI_TaxID=175788 {ECO:0000313|EMBL:KAK3551139.1, ECO:0000313|Proteomes:UP001274896};
RN [1] {ECO:0000313|EMBL:KAK3551139.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Male_cb2023 {ECO:0000313|EMBL:KAK3551139.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAK3551139.1};
RA Bian C.;
RT "Male Hemibagrus guttatus genome.";
RL Submitted (JUN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK3551139.1}.
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DR EMBL; JAUCMX010000003; KAK3551139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAE0RDT8; -.
DR Proteomes; UP001274896; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR CDD; cd20024; FH_FOXJ2-like; 1.
DR FunFam; 1.10.10.10:FF:000135; forkhead box protein G1; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR045912; FOXJ2/3-like.
DR InterPro; IPR000868; Isochorismatase-like_dom.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46078:SF4; FORKHEAD BOX J2; 1.
DR PANTHER; PTHR46078; FORKHEAD BOX PROTEIN J2 FAMILY MEMBER; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP001274896};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 176..253
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 176..253
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 140..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..171
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..316
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 75052 MW; BE31C6D74FBDA3B6 CRC64;
MLTESVENEL KSLGSPKQAI LCGIEAQACI ACTTYDLLER GMEVHIVADA VSARSQTDRL
FALSRLKQSG AFLTTTESVM LQLVQDAKHP NFKEVPPHYK RKNSMVYSGL VAATSLTMTS
ELDSSLTSID WLPNLGMGSL RSGKERGERK RERGRERDTP PSIPSSSPPP NSSKGKPPHS
YATLIAMAIS SAPERKLSLN DIYTWISDTF PFYSRAGRGW KNSIRHNLSL NKCFRKVPRP
QSDPGKGSYW TMDGPPDQYQ SRGAKRPYPT SDEETEVTEK PPLTMDKTHI RQAEPLPPAD
IKTTLAPPPC KRPPPALLNT APAASVPSAE QPLRFSFTDL NLPDLYNSFQ SLCRSVRERV
TSQSDVSSLL GIPGDIAPLH TPTLPPLSPH PCPSTIPPTH LVTSVNTSTN LTPNVNPSFP
SNQNVEPDRL LHNNIVPTDW FSNAESLRES FRIASSLDWS NIDLTNHPDL VESMRQAELC
DWALDPAVFT SLCDSLNRFF TRRGIIGSVS GSSSTLSQIA SPLTNMPLGA HPALSHLTQP
SPLSLPPQLP HCSGSPCVQS HRKTLTPQNH SQNSQRNLEP QPAVSQPLPS NAGKMGKQKD
FDKGQIVMAR PLDQSISKTA ALVGCSRSAV TKFIHSFIVY RLSELFSAIP AQPLTPRNRP
PMKQLHSNSE EIQDDFDWDS LIV
//
