ID A0AAE0SC31_9BIVA Unreviewed; 2668 AA.
AC A0AAE0SC31;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 10-JUN-2026, entry version 7.
DE RecName: Full=Nuclear receptor corepressor 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CHS0354_017117 {ECO:0000313|EMBL:KAK3589149.1};
OS Potamilus streckersoni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Heteroconchia; Palaeoheterodonta; Unionida; Unionoidea;
OC Unionidae; Ambleminae; Lampsilini; Potamilus.
OX NCBI_TaxID=2493646 {ECO:0000313|EMBL:KAK3589149.1, ECO:0000313|Proteomes:UP001195483};
RN [1] {ECO:0000313|EMBL:KAK3589149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CHS0354 {ECO:0000313|EMBL:KAK3589149.1};
RX PubMed=33570560; DOI=10.1093/gbe/evab029;
RA Smith C.H.;
RT "A High-Quality Reference Genome for a Parasitic Bivalve with Doubly
RT Uniparental Inheritance (Bivalvia: Unionida).";
RL Genome Biol. Evol. 13:evab029-evab029(2021).
RN [2] {ECO:0000313|EMBL:KAK3589149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CHS0354 {ECO:0000313|EMBL:KAK3589149.1};
RC TISSUE=Mantle {ECO:0000313|EMBL:KAK3589149.1};
RA Smith C.H.;
RT "Developing a high-quality reference genome for a parasitic bivalve with
RT doubly uniparental inheritance (Bivalvia: Unionida).";
RL Genome Biol. Evol. 0:0-0(2021).
RN [3] {ECO:0000313|EMBL:KAK3589149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CHS0354 {ECO:0000313|EMBL:KAK3589149.1};
RC TISSUE=Mantle {ECO:0000313|EMBL:KAK3589149.1};
RA Smith C.H.;
RL Submitted (MAY-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N-CoR nuclear receptor corepressors family.
CC {ECO:0000256|ARBA:ARBA00010097}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK3589149.1}.
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DR EMBL; JAEAOA010001049; KAK3589149.1; -; Genomic_DNA.
DR Proteomes; UP001195483; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:TreeGrafter.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-ARBA.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProtKB-ARBA.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR CDD; cd00167; SANT; 1.
DR FunFam; 1.10.10.60:FF:000026; Nuclear receptor corepressor 2 isoform 1; 1.
DR Gene3D; 1.20.5.430; -; 1.
DR Gene3D; 1.20.58.1880; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeodomain-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR051571; N-CoR_corepressor.
DR InterPro; IPR031557; N-CoR_GPS2_interact.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR13992; NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR; 1.
DR PANTHER; PTHR13992:SF39; SMRTER, ISOFORM G; 1.
DR Pfam; PF15784; GPS2_interact; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF27579; NCOR1_N; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP001195483}.
FT DOMAIN 475..521
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 751..801
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 754..805
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 758..805
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1523..1547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1582..1786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1835..1956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1991..2173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2185..2668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..559
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..607
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..854
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..921
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..980
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 981..1018
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1069
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1134..1144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1216..1240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1315..1326
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1359..1370
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1373..1397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1528..1540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1637..1646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1680..1691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1699..1716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1717..1734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1742..1755
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1855..1871
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1891..1909
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1918..1953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1998..2012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2013..2024
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2064..2090
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2136..2147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2218..2232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2266..2288
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2297..2313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2331..2344
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2430..2444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2498..2507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2536..2547
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2563..2580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2604..2630
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2668 AA; 293740 MW; 2919D8B10AC6EB2B CRC64;
MSNRPSGDRG PGGSPHDAGA SPYKRPRPQS PSATIQRSGT YVYSTQDPRY SGMHASQAST
VPTSYSLYTP HYPTQPEHVR DYGRLSRNDE QLLQQYKRRP TLLQEYHHGH TSNVDRSRYG
PADPGYSQRF HQDNMGNLQS HQGTPLASSS TDLGGPQTPK RPRLAIDRPD LTQPLRIDTK
EAEPKREPAY NPQVEAISPT LPPEETNKAS KVKDDLLQGI SRFDREIGIV EQQIIKLNRK
QQQLEEEAAR PPEEKPVIPD LPVPETKHLQ SIAQIIYAEN RKKAEEAHSI FAKLGPKIEL
PLYNQPSDTA IYHENKKKFQ TFKKSLILFF KRRHQARKIR ERYLTERYDQ LMQVWIKKIE
KAENNPKKKT KDARLREYFE KVFPEIKKSR EEKERFSRVG SRSGMGVYAR SEAEFEQIMD
GLHEQEEEDK KMRSYAVIPP MMLDARQRKL RFINNNGFIE DPMEEYKERK HINCWSIHEK
QIFKEKYLQH PKNFALIATY LDKKTTADCV QFYYQTKKSE NYKQLLRKQN AKKKRQLAKS
QARAQEEVVE GTSSSSVQEP MTTQTSAEGD AGDKTTDNVV STSIGGDVVI KKEEKEEDMA
ADESSDDNES RDTEVGGSHQ CALCKTVLED FVLSRPLNKS NCETYGLNEA DLRPDMRVCT
SCRCKSVRRR YTTCPVPTCK TPRRRVKRLR PLPQKWVELP AEIKDPIMQE LQLTDDLNKC
CSACFNRIAR KLGTNPHTNE PVVSLVQEPP EEVTETSRWT EEEMEVAQRG LRDHGKDWSA
IASMVGTKSE AQCKNFYFNY KKKLNLEAVV QEHKDKEEDK RTVSICESVA STATVPSEGE
DNSSNDEDNA DSDDSGTASA PSPRPLQIED QDEKGDENQT GAGDMGNQSG DLAENLASKK
PLSASQGSLR SIPDNDSSAT MSADEAPAPH HDRNSQSGLY TSIGPTETRV TSPHTSGIPM
PGARQFQGSS ASLGQVQSVD QSQPMGSQSS SRPGSRPGSA YGSGHQGQSP SSRPSSRPSS
HEVPIMKDQG QSQMGVIDFS HASSGYSQFP TMSSREAMQQ PLRPSSSLSE PGMRVMSPHA
GGTQGYNAPG PRNLSPQPQM NAFQATDKKH SKATCVRDLI HTAIERNLSQ NNDRTTEAAS
EQRQRAVTSE PVYPVRSGGL LSSQFLPQDL RKREPSRASP YPADYQRGSP YLTGTRGPDA
RDLAVSRPNQ EYEVQDLSRR SQDLDKGPHG YKGDPRDFHS QPKSGESFTR QMEEAQNMSK
IGTIVTPPPA HSHRPTLYGT GDALALKSRT PEGHDKQMLM YSGAGDRQSP AIRVSTPSTS
PYSIITQGDP QSRQLGPKVG IPGPPPLISR GSSPKHPRSP PGGPHLPPPS GSITHGTPVS
HPATTSAPSS VSRQAYESTH GPRLQYHGSI TQGTPVRDAH GAGRGLQMST EGMAVRMPYM
RILEPGQIPP GGHAQMYEQQ ILADQKRLAE QQHQQLRMSQ ANSVSGPSGH YSQYAYNTAE
SYSNNSTKQT IINDFVTARQ MRIQTSPTEK DPRNSPRGKE MGAAPTQKVY PPQVVDPRLV
HTIHPFVTSS GVVLGQNQMV QQGDSRMMGS SRVSPRPSQP HNTNTSPRDE KNSWMMGPRA
SLAPSSGIHP GHIPYQVPTS RPSITEGTGR PSVITDTPPT SSDDRYNHPP DSSGAHRGQS
PRQGYSLSIP QSVEVHRQSP GNTNYPQHYQ SLTSAQDRGH WERDQIDQRS RYEPRMMGQS
GREYDREWTT DKPKDIMSLQ YQKTRPEPPT SAPGGTASES SRKSPKMQID AAFLHALAPD
VRLIQPVKSG DTTRTKHHLT AANLIDAIIV HQINQSPDCP KPDPSESITA RLAASSPSNR
QSSEDNVTTS KATEKKSPTA SQPAGKKRWI TPASSTSSSP SSTPLPTSSK PEQEREQSTY
GASTGTGQSG FSTAADSSSK TVISEATGRS RQMMTLGDHI NSIILLDYEK KSTSEEKSSF
SNLLNKINVA EEEEKNNSSK PLQDIPSSSQ GISSAHHTPS SGSSRTVSPK GDIQADSARS
RPQPGGGVSS YSHLGHKRWK MIQESEQASS SAQGSEDSSS EVVSQSSHSG LSEEHGHRSI
QGQDSDHHMI KPDQSYSPKG KRHAASMEPI SPPGQADSSS TTMQGSSGDP KGTISMGPRR
FQNQPPDVSV SPLLYVRNKI EECLQDEDNR MTSGQQHSQH SRMSHLQIPQ QQQQQQQIHG
QRTQTPASSQ MGGQRDPSPG VLPKQPRQLD MYLGSMESHL SSSGQSKPDP SASPTSSSQT
SPDQRQSPAD QEEDSSKMMN SHQKAQPHSQ SHSPVPLGDH GSNGGQGAQH PHAHGKKRMI
TRQRVRYDPD NSGVKITLAT TTREHQPKGA PSLMPETQRA STSSDKKGPK SLYDFPDSPD
DDNILRRPPS SYMALNSTTR SPRRGVVDST DSRSMRSSAD ETSRGQEGSA ENSGDLLDSQ
GREATSFERD NEAQGVERYG ASRDEHSVDT SYMDPSGPKS NRGGSRKQSN EIDDGSNISH
TSADSTDRLV VDDIDSSSTT GDVSSGSQLL RRGSKSSRDS EGSTDFTTAL DHVSQSQQAD
SSMHSLSGHS HRSRSPRSSE SHFPHSSSDL PTSMASSIQS SSGLGYSSRG RQNSRMAADS
ESGQESRDTD SYPLLSSQYE TLSEEEEL
//
