ID A0AAE0UT91_9TELE Unreviewed; 717 AA.
AC A0AAE0UT91;
DT 29-MAY-2024, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2024, sequence version 1.
DT 28-JAN-2026, entry version 8.
DE RecName: Full=Oxysterol-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=QTP70_000657 {ECO:0000313|EMBL:KAK3518441.1};
OS Hemibagrus guttatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Bagridae; Hemibagrus.
OX NCBI_TaxID=175788 {ECO:0000313|EMBL:KAK3518441.1, ECO:0000313|Proteomes:UP001274896};
RN [1] {ECO:0000313|EMBL:KAK3518441.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Male_cb2023 {ECO:0000313|EMBL:KAK3518441.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAK3518441.1};
RA Bian C.;
RT "Male Hemibagrus guttatus genome.";
RL Submitted (JUN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK3518441.1}.
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DR EMBL; JAUCMX010000017; KAK3518441.1; -; Genomic_DNA.
DR AlphaFoldDB; A0AAE0UT91; -.
DR Proteomes; UP001274896; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 2.40.160.120:FF:000005; Oxysterol-binding protein; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP001274896}.
FT DOMAIN 350..463
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 612..717
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 277..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 77792 MW; F46981FD97D0B0AB CRC64;
MNSEEEFYDA ETGLESDDSC EVSFKDAPGF ESKQASNGCV RSENGVWKQR TTLPAPMFTR
HDFSIWGFLK KCIGMELSKI TMPVVFNEPL SFLQRLTEYM EHTYLIHKAC TLSDSIERMQ
LVAAFAVSAV ASQWDRTGKP FNPLLGETYE LIREDDGYRL ISEQVGHHPP ISAFHSESLT
QDFQFHGSIY PKLKFWGKSV EAEPKGTMTL ELSKHKEAYT WTNPMCCVHN VIIGKLWIEQ
YGTVEIVNHS KKKRRIIYGK WTECLYAIDP KVYETNKKTE KKSGDSKKHK QELNTGNAAD
DADEMPEVQE TVTMIPGSTL LWRITARPAH SDQMSSGALF PSLVSGSRGS SSKYLVEFRA
GKMSLKGSIV TPDKRKGQVY IQQTDDSLIH FCWKDRTTGN VEDDLIIFPD DCEFKRVSQC
TTGRVYVLKF KAGSKRLFFW MQEPKTDKDD EYCRKVNEYL NNPPIPGSLG GGGSSHELSA
LGGEGGLQSL LGNVSHNQLM QLIGPTGLGG LGGLGALAGP GLASLLGGSV PATSSSSSSQ
STAVTPSSTS AATRLNSSQV PTTPTTPSAT TGASPVTTPS TPAAPAPSAG ATSPTQPIQL
SDLQNILATM NVPAAGQGVD LASVLTPEIM APILANAEIQ QRLLPFLPSG ESLPQSTDEL
HNTLTSPQFQ QAMSLFSSAL ASGQLGPLMN QFGLPSEAVD AANKGGKCRS ICQGYGR
//
