ID A0AAJ0LZG2_9PEZI Unreviewed; 634 AA.
AC A0AAJ0LZG2;
DT 24-JUL-2024, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2024, sequence version 1.
DT 28-JAN-2026, entry version 7.
DE SubName: Full=Dfp1/Him1, central region-domain-containing protein {ECO:0000313|EMBL:KAK3303406.1};
GN ORFNames=B0T15DRAFT_401720 {ECO:0000313|EMBL:KAK3303406.1};
OS Chaetomium strumarium.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=1170767 {ECO:0000313|EMBL:KAK3303406.1, ECO:0000313|Proteomes:UP001273166};
RN [1] {ECO:0000313|EMBL:KAK3303406.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 333.67 {ECO:0000313|EMBL:KAK3303406.1};
RX PubMed=37820761;
RA Hensen N., Bonometti L., Westerberg I., Brannstrom I.O., Guillou S.,
RA Cros-Aarteil S., Calhoun S., Haridas S., Kuo A., Mondo S., Pangilinan J.,
RA Riley R., LaButti K., Andreopoulos B., Lipzen A., Chen C., Yan M., Daum C.,
RA Ng V., Clum A., Steindorff A., Ohm R.A., Martin F., Silar P., Natvig D.O.,
RA Lalanne C., Gautier V., Ament-Velasquez S.L., Kruys A., Hutchinson M.I.,
RA Powell A.J., Barry K., Miller A.N., Grigoriev I.V., Debuchy R.,
RA Gladieux P., Hiltunen Thoren M., Johannesson H.;
RT "Genome-scale phylogeny and comparative genomics of the fungal order
RT Sordariales.";
RL Mol. Phylogenet. Evol. 189:0-0(2023).
RN [2] {ECO:0000313|EMBL:KAK3303406.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 333.67 {ECO:0000313|EMBL:KAK3303406.1};
RG Lawrence Berkeley National Laboratory;
RA Mondo S.J., Hensen N., Bonometti L., Westerberg I., Brannstrom I.O.,
RA Guillou S., Cros-Aarteil S., Calhoun S., Haridas S., Kuo A., Pangilinan J.,
RA Riley R., Labutti K., Andreopoulos B., Lipzen A., Chen C., Yanf M.,
RA Daum C., Ng V., Clum A., Steindorff A., Ohm R., Martin F., Silar P.,
RA Natvig D., Lalanne C., Gautier V., Ament-Velasquez S.L., Kruys A.,
RA Hutchinson M.I., Powell A.J., Barry K., Miller A.N., Grigoriev I.V.,
RA Debuchy R., Gladieux P., Thoren M.H., Johannesson H.;
RL Submitted (JUN-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAK3303406.1}.
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DR EMBL; JAUDZG010000006; KAK3303406.1; -; Genomic_DNA.
DR RefSeq; XP_062719186.1; XM_062865127.1.
DR AlphaFoldDB; A0AAJ0LZG2; -.
DR GeneID; 87883956; -.
DR Proteomes; UP001273166; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP001273166};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 582..631
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..399
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..541
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 70330 MW; C7734D02FBC54331 CRC64;
MSTRRVPLSY SNPNILNSPA RVGSAVGNGI KKGRTHAESV REEPYGQPPP AKRQMIDRGV
ASPTATRATR AIVHRTASRA TGATTATTNR ATHTTTYGHT QEELISLQAW TTHTRARFPK
MVFYFESIPD ELRPKLAKQV SRLGAREEKF FSIDITHVVT TRTIPSEKPK GEQDGRAEGQ
GDREQPRTID PSLLNRPADP TRRKLVFDTA SSGRPGAPKT RSVDVLDRAR EMGKKIWSLE
KLQKILKMLL ETDPRLAAAG GYDHGSTQST TTKVATGHPD IKRLLDEERV HGPSDRDPTV
PGKELYTFKG YYIYVYDLEE KTKPIMAREF RKGADPTDGE WPQFRSASHG RCPFVIDENY
DAAEKEDRER DRARAKARAA RAAAEDAVDP AAQQPKASEA PPPKPATGKR TLSQMEDGHN
RGMANVRETV LLDRSKISNP PVFDFQSQNA FVSQAKAGRF VAGEPVASGL QPSNITSAIR
SQMISSTTGG VLGAKAGTSK EIHGLQRKVV LQRTGTSAQA QDLSSVRRGE TSHNGTTFGR
SASVTGVTSR RLDPFVDEER LKEQEKLRRT VSVPVSQPKP KRDPKPGYCE NCQDKFADFE
EHIVSRKHRK FAENDENWTQ LDALLSQLKR VPRY
//
