ID A0AAJ0XB15_9GAMM Unreviewed; 352 AA.
AC A0AAJ0XB15;
DT 24-JUL-2024, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2024, sequence version 1.
DT 28-JAN-2026, entry version 7.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703, ECO:0000256|NCBIfam:TIGR01128};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417, ECO:0000256|NCBIfam:TIGR01128};
GN ORFNames=CKO40_15410 {ECO:0000313|EMBL:MBK1705903.1};
OS Halochromatium glycolicum.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Chromatiales; Chromatiaceae; Halochromatium.
OX NCBI_TaxID=85075 {ECO:0000313|EMBL:MBK1705903.1, ECO:0000313|Proteomes:UP001296776};
RN [1] {ECO:0000313|EMBL:MBK1705903.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 11080 {ECO:0000313|EMBL:MBK1705903.1};
RA Imhoff J.F., Rahn T., Kuenzel S., Neulinger S.C.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBK1705903.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 11080 {ECO:0000313|EMBL:MBK1705903.1};
RX PubMed=33375353;
RA Imhoff J.F., Rahn T., Kunzel S., Keller A., Neulinger S.C.;
RT "Osmotic Adaptation and Compatible Solute Biosynthesis of Phototrophic
RT Bacteria as Revealed from Genome Analyses.";
RL Microorganisms 9:0-0(2020).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) +
CC diphosphate; Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-
CC COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112;
CC EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00049244};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBK1705903.1}.
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DR EMBL; NRSJ01000030; MBK1705903.1; -; Genomic_DNA.
DR RefSeq; WP_200347190.1; NZ_NRSJ01000030.1.
DR AlphaFoldDB; A0AAJ0XB15; -.
DR Proteomes; UP001296776; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:TreeGrafter.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP001296776};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 20..144
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 221..334
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 352 AA; 38091 MW; 3C2D1B7CD603AA33 CRC64;
MPLPPQQLPQ RLTRELAPVY LIAGSEPLQL NEAADAVRSA ARKRGFNERE VLETGPDFDW
GSLAGAMGSL SLFAERRLIE LRVGTPKSGT KGDGVGREGA DAIRRCCEQP SDDVLLLILG
PNLDWKGLKA KWVQRIEQIG VVVQVRELQG RQLSQWLAER LRRAGFTPTA EAVALLSERV
EGNLLAADQE ISKLRLALEP GPLDADGLMA AVSDSARYGV FDLADAAVAG DRARVARVLA
GLRAEGTAEP LVLWALAREV RKLAAVAFAR ARQQPLGPIL KAHQVWESRR QTTLAAADRI
GLAALWDLVM RCADADEAIK GRVDANPWQL LEGIAEGLAA PGSARPRIDR IA
//
