ID A0AAY4EPX9_9TELE Unreviewed; 161 AA.
AC A0AAY4EPX9;
DT 05-FEB-2025, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2025, sequence version 1.
DT 10-JUN-2026, entry version 6.
DE RecName: Full=Probable ribosome biogenesis protein RLP24 {ECO:0000256|ARBA:ARBA00039784};
DE AltName: Full=Ribosomal L24 domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042993};
GN Name=RSL24D1 {ECO:0000313|Ensembl:ENSDCDP00010059720.1};
OS Denticeps clupeoides (denticle herring).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes;
OC Denticipitoidei; Denticipitidae; Denticeps.
OX NCBI_TaxID=299321 {ECO:0000313|Ensembl:ENSDCDP00010059720.1, ECO:0000313|Proteomes:UP000694580};
RN [1] {ECO:0000313|Ensembl:ENSDCDP00010059720.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Wellcome Sanger Institute Data Sharing;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDCDP00010059720.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDCDP00010059720.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC Ensures the docking of GTPBP4/NOG1 to pre-60S particles.
CC {ECO:0000256|ARBA:ARBA00037035}.
CC -!- SUBUNIT: Associated with nucleolar and cytoplasmic pre-60S particles.
CC At the end of biogenesis it dissociates from cytoplasmic pre-60S
CC particles and is likely to be exchanged for its ribosomal homolog,
CC RPL24. {ECO:0000256|ARBA:ARBA00047058}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL24 family.
CC {ECO:0000256|ARBA:ARBA00005647}.
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DR RefSeq; XP_028813227.1; XM_028957394.1.
DR AlphaFoldDB; A0AAY4EPX9; -.
DR Ensembl; ENSDCDT00010070448.1; ENSDCDP00010059720.1; ENSDCDG00010033333.1.
DR GeneID; 114766549; -.
DR GeneTree; ENSGT00950000183105; -.
DR Proteomes; UP000694580; Chromosome 17.
DR GO; GO:0005730; C:nucleolus; IEA:TreeGrafter.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:TreeGrafter.
DR CDD; cd00472; Ribosomal_L24e_L24; 1.
DR FunFam; 2.30.170.20:FF:000001; probable ribosome biogenesis protein RLP24; 1.
DR Gene3D; 2.30.170.20; Ribosomal protein L24e; 1.
DR InterPro; IPR038630; L24e/L24_sf.
DR InterPro; IPR056366; Ribosomal_eL24.
DR InterPro; IPR000988; Ribosomal_eL24-rel_N.
DR InterPro; IPR023442; Ribosomal_eL24_CS.
DR InterPro; IPR011017; TRASH_dom.
DR PANTHER; PTHR10792; 60S RIBOSOMAL PROTEIN L24; 1.
DR PANTHER; PTHR10792:SF8; RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED; 1.
DR Pfam; PF01246; Ribosomal_L24e; 1.
DR SMART; SM00746; TRASH; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS01073; RIBOSOMAL_L24E; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694580};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 6..44
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
SQ SEQUENCE 161 AA; 19289 MW; 0DC7942B51F87075 CRC64;
MRIEKCYFCS GPLYPGHGMM FVRNDCKVFR FCKSKCHKNF KKKRNPRKTR WTKAFRKASG
KELTVDNSLE FEKRRNIPVK YKRELWNKTV EAMKKVEAIK QKRQARFIMN RLKKGKELEK
EEAIVEVKKN IHLIRAPHAG KAKQLEEKMV QKLQEDVEMD D
//
